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GenomicsBromodomain-dependent stage-specific male genome programming by Brdt
This SuperSeries is composed of the following subset Series: GSE39908: Bromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq] GSE39909: Bromodomain-dependent stage-specific male genome programming by Brdt [Illumina BeadArray] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39910 | biostudies-arrayexpress
GenomicsChromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B [ChIP-Seq]
The conversion of male germ cell chromatin to a nucleoprotamine structure is fundamental to the life cycle yet the underlying molecular details remain obscure. Here we show that an essential step is the genome-wide incorporation of TH2B, a histone H2B variant of hitherto unknown function. Using mous...
ORGANISM(S): Mus musculus 
2013-10-18 | E-GEOD-45915 | biostudies-arrayexpress
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39908 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of immortalized N/TERT keratinocytes stimulated with IFNγ
Inflammasomes are multicomplex proteins which drive pro-inflammatory cytokine responses and pyroptosis in innate immunity. Of which, the NLRP3 inflammasome is the most extensively studied, especially in myeloid immune cells such as macrophages. Conversely, the regulation of NLRP3 in non-immune cell ...
ORGANISM(S): Homo sapiens 
2025-10-30 | E-MTAB-15754 | biostudies-arrayexpress
UnknownPrognostic Factors of Late-onset Hearing Loss in Infants With Congenital Cytomegalovirus and Normal Audiologic Assessment at Birth.
Not available
S-EPMC12688458 | biostudies-literature
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