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TranscriptomicsExpression data from cultured human ovarian carcinoma cell lines with and without Cisplatin treatment
Chemo-resistance to platinum such as cisplatin is critical in the treatment of ovarian cancer. Recent evidences have linked epithelial-mesenchymal transition (EMT) with the drug resistance as a contributing mechanism. The current study explored the connection between cellular responses to cisplatin ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-47856 | biostudies-arrayexpress
TranscriptomicsGene expression data of ovarian cancer from Singapore
A collection of 100 ovarian cancer sample gene expression data from Singapore. Frozen archival epithelial ovarian cancer tumors samples from Department of Obstetrics & Gynecology, National University of Singapore dated from 2006 to 2014 were collected and subjected to microarray analysis.
ORGANISM(S): Homo sapiens 
2016-01-10 | E-GEOD-69207 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of LCM captured breast cancer cells
The purpose of this study is to obtain comprehensive gene expression profiles in breast cancer. Mammary gland cells were specifically isolated from 433 clinical tissue samples by laser capture microdissection (LCM). Total RNAs were extracted from LCM captured samples. We investigated gene expression...
ORGANISM(S): Homo sapiens 
2014-09-16 | E-GEOD-54002 | biostudies-arrayexpress
TranscriptomicsEMT-induced stemness and tumorigenicity are fueled by an oncogenic EGF/Ras pathway
Pre-EMT GIF14 cells treated with TGF-M-NM-21 Total RNA obtained from isolated GIF-14 cells from untreated and TGF-M-NM-21-treated sample
ORGANISM(S): Mus musculus 
2014-02-19 | E-GEOD-44055 | biostudies-arrayexpress
GenomicsDNAseq data from human ovarian carcinoma cell lines subjected to shRNA TRC1.0 library
The hallmark of human cancer is heterogeneity, mirroring the complexity of genetic and epigenetic alterations acquired during oncogenesis. We extracted DNA of 14 cultured human ovarian carcinoma cell lines subjected to pooled shRNA screen using TRC 1.0 library, and performed DNAseq. 14 ovarian carc...
ORGANISM(S): Homo sapiens 
2013-05-21 | E-GEOD-45420 | biostudies-arrayexpress
TranscriptomicsExpression data from cultured human ovarian carcinoma cell lines
The hallmark of human cancer is heterogeneity, mirroring the complexity of genetic and epigenetic alterations acquired during oncogenesis. We extracted RNA of 34 cultured human ovarian carcinoma cell lines and performed expression microarrays so that cultured cell lines can represent in vivo human ...
ORGANISM(S): Homo sapiens 
2013-05-21 | E-GEOD-28724 | biostudies-arrayexpress
TranscriptomicsGrainyhead-like 2 (GRHL2) maintains the epithelial status of ovarian cancer through miR-200-ZEB1 regulatory networks (expression)
Epithelial ovarian cancer (EOC) is clinically heterogeneous, comprising different histological and biological subtypes. Multiple studies have implicated epithelial-mesenchymal transition (EMT), a biological process by which polarized epithelial cells convert into a mesenchymal phenotype, to contribu...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-71017 | biostudies-arrayexpress
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