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Reprogrammed cells are reverted to non reprogrammed cell fate in a maturation step of reprogramming. Cell fate changes during reprogramming from fibroblasts to iPSC , N=60 fibrobalst lines, N=13 Undifferentiated pluripotent stem cells, N=16 Nascent reprogrammed cells, N=31
ORGANISM(S): Homo sapiens 
Inducing mitochondrial uncoupling (mUncoupling) is an attractive therapeutic strategy for treating metabolic diseases because it leads to calorie-wasting by reducing the efficiency of oxidative phosphorylation (OXPHOS) in mitochondria. Here we report a safe mUncoupler, OPC-163493, which has unique p...
2019-05-24 | MTBLS836 | MetaboLights
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