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UnknownIs chloroplastic class IIA aldolase a marine enzyme?
Not available
S-EPMC5113842 | biostudies-literature
UnknownCryo-EM structure of the gastric proton pump complexed with revaprazan
Not available
EMPIAR-11057 | biostudies-other
TranscriptomicsmTOR inhibitors synergistically induce regression, reversal of gene expression and autophagy in hepatocellular carcinoma
The mTOR-allosteric inhibitor, RAD001, in combination with a PI3K/mTOR ATP-site competitive inhibitor, BEZ235, causes gene reprogramming, autophagy and tumor regression, in a mouse model approximating human HCC with poor prognosis, leading to an investigator Phase 1B-2 clinical trial. Comparative st...
ORGANISM(S): Mus musculus 
2012-07-11 | E-GEOD-37129 | biostudies-arrayexpress
TranscriptomicsAcyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma development
Gene expression profiling in non tumor lesion in the liver of patients prior to administering peretinoin was unrelated to the clinical outcome, however, gene expression profiling 8 weeks after starting peretinoin therapy significantly predicted the recurrence of HCC Peretinoin, a member of the acycl...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-29302 | biostudies-arrayexpress
TranscriptomicsSerial gene expression profiling in the liver of Pdgf-c Tg mice that developed hepatic fibrosis and tumors
Over expression of PDGF-C in mouse liver resulted in the progression of hepatic fibrosis, steatosis and the development of HCC; this mouse model closely resembles the human HCC that is frequently associated with hepatic fibrosis. Peretinoin (generic name; code, NIK-333), developed by the Kowa Compan...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-31431 | biostudies-arrayexpress
UnknownGenetic insights into ossification of the posterior longitudinal ligament of the spine.
Not available
S-EPMC10353864 | biostudies-literature
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