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TranscriptomicsDifference in gene expression between WT (Col-0) and atxrn4-3 mutant under non-stress and heat stress condition
Arabidopsis 5’-3’ exoribonuclease, AtXRN4, a homolog of yeast Xrn1p, functions in degradation of uncapped RNAs after de-capping step. While Xrn1p-dependent on plant XRN4’s targets for degradation is still limited. For understanding biological function of AtXRN4, we tested survivability of atxrn4 mut...
ORGANISM(S): Arabidopsis thaliana 
2015-07-14 | E-GEOD-66369 | biostudies-arrayexpress
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
UnknownMassive extended streamers feed high-mass young stars.
Not available
S-EPMC12366688 | biostudies-literature
ProteomicsCross-linking MS analysis of HIV-2 Vpx-PHD3 protein interaction
This dataset presents chemical crosslinking mass spectrometry (CL-MS) analysis of protein-protein interactions between HIV-2 Vpx and PHD3. The experimental data includes MS spectra obtained from protein complexes comprising recombinant Vpx and PHD3 crosslinked using DSBU under physiological conditio...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059241 | JPOST Repository
ProteomicsPHD3-mediated HIV-2 Vpx peptide hydroxylation
This dataset contains comparative mass spectrometry analysis investigating proline hydroxylation of synthetic HIV-2 Vpx peptides under two conditions: with and without PHD3 enzyme treatment. The analysis was performed using a high-resolution mass spectrometer coupled to a nano-LC system. The dataset...
ORGANISM(S): Human Immunodeficiency Virus 2 
2025-04-03 | PXD059242 | JPOST Repository
UnknownGenetic insights into ossification of the posterior longitudinal ligament of the spine.
Not available
S-EPMC10353864 | biostudies-literature
ProteomicsIntegrated Tandem Affinity Protein Purification Using the Polyhistidine plus Extra 4 Amino Acids (HiP4) Tag System
Interactome analysis of HBx using a novel tag system (HiP4-tag system).
ORGANISM(S): Homo Sapiens (human) 
2023-02-28 | PXD036256 | JPOST Repository
ProteomicsIntegrated Tandem Affinity Protein Purification Using the Polyhistidine plus Extra 4 Amino Acids (HiP4) Tag System２
Interactome analysis of TARDBP (TDP-43) using a novel tag system (HiP4-tag system).
ORGANISM(S): Homo Sapiens (human) 
2023-02-28 | PXD038445 | JPOST Repository
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