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TranscriptomicsExpression data from Arabidopsis root in response to boron limitation
Boron is essential for plants, and boron availability in soil is an important determinant of agricultural production. Boron availability in soil is limited at many regions in the world, including Japan. Under boron deficient conditions, leaf expansion and root elongation, apical dominance, flower de...
ORGANISM(S): Arabidopsis thaliana 
2013-11-13 | E-GEOD-52208 | biostudies-arrayexpress
TranscriptomicsDown-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients
MicroRNAs are a family of 19- to 25-nucleotides noncoding small RNAs that primarily function as gene regulators. Aberrant microRNA expression has been described for several human malignancies, and this new class of small regulatory RNAs has both oncogenic and tumor suppressor functions. Despite th...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14772 | biostudies-arrayexpress
TranscriptomicsThe Chimeric Oncoprotein TLS-CHOP Represses Expression of the Anticancer Cytokine MDA-7/IL-24 in Myxoid Liposarcoma Cells
The TLS-CHOP fusion protein is found in the majority of human myxoid liposarcomas (MLS), and is thought to have oncogenic functions. Until now, however, the molecular function of TLS-CHOP for oncogenesis is still elusive. In this report, we have revealed that knockdown of TLS-CHOP by specific siRN...
ORGANISM(S): Homo sapiens 
2013-12-27 | E-GEOD-33616 | biostudies-arrayexpress
TranscriptomicsTLS-CHOP Fusion Oncoprotein Regulates MicroRNA-486 in Human Myxoid Liposarcoma
MicroRNAs (miRNAs, miRs) are small noncoding RNAs, which control or are controlled by the dysregulation of multiple protein-coding oncogenes or tumor suppressor genes, play important roles in carcinogenesis. Myxoid liposarcomas (MLS) are characterized by t(12;16)(q13;p11) translocation and expressio...
ORGANISM(S): Mus musculus 
2013-03-23 | E-GEOD-36966 | biostudies-arrayexpress
TranscriptomicsInterferon signaling related gene expression and clinical outcome of chronic hepatitis C
Chronic hepatitis C (CH) frequently developed liver cirrhosis and hepatocellular carcinoma without suitable treatment. However, peginterferon(IFN) and ribavirin therapy (combination therapy), which is present standard therapy, is imperfect effect because of several side effect. We attempt to catalog...
ORGANISM(S): Homo sapiens 
2010-02-10 | E-GEOD-20119 | biostudies-arrayexpress
TranscriptomicsAdipocyte differentiation with or without Bilberry and anthocyanidins
Metabolic syndrome is an important public concern and demand for effective therapeutic strategies. Abdominal obesity, especially an increase in the visceral adipose tissue, is the main cause of this syndrome. Flavonoids are expected to improve risk factors for metabolic syndrome. Bilberry, original ...
ORGANISM(S): Mus musculus 
2011-04-01 | E-GEOD-21157 | biostudies-arrayexpress
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