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Metabolomics13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ metabolism during hypothermic machine perfusion of kidneys
Background: The aim of this study is to determine the feasibility of using Nuclear Magnetic Resonance (NMR) tracer studies (13C-enriched glucose) to detect ex vivo de novo metabolism in the perfusion fluid and cortical tissue of porcine kidneys during hypothermic machine perfusion (HMP). Methods: Por...
2017-10-16 | MTBLS367 | MetaboLights
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MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamine...

2022-10-31 | MTBLS5381 | MetaboLights
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UnknownAntipsychotic <b>Effects on Cortical Morphology in Schizophrenia and Bipolar Disorders.
Not available
S-EPMC7758211 | biostudies-literature
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UnknownTargeting Trop2 by Bruceine D suppresses breast cancer metastasis by blocking Trop2/β-catenin positive feedback loop.
Not available
S-EPMC10982870 | biostudies-literature
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Genomics,MultiomicsFramingham Cohort

<b>Startup of Framingham Heart Study. Cardiovascular disease (CVD) is the leading cause of death and serious illness in the United States. In 1948, the Framingham Heart Study (FHS) -- under the direction of the National Heart Institute (now known as the National Heart, Lung, and Blood Institut...

phs000007.v17.p6 | EGA
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UnknownAssociation Between Bipolar Disorder and Low Bone Mass: A Cross-Sectional Study With Newly Diagnosed, Drug-Naive Patients.
Not available
S-EPMC7299052 | biostudies-literature
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UnknownCognitive Remediation in Patients With Bipolar Disorder: A Randomized Trial by Sequential tDCS and Navigated rTMS Targeting the Primary Visual Cortex.
Not available
S-EPMC11659637 | biostudies-literature
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UnknownPreclinical Profile of AB-423, an Inhibitor of Hepatitis B Virus Pregenomic RNA Encapsidation.
Not available
S-EPMC5971612 | biostudies-literature
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UnknownChemoprevention of gastric cancer by celecoxib in rats.
Not available
S-EPMC1774922 | biostudies-literature
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UnknownHydroxy-Selenomethionine Mitigated Chronic Heat Stress-Induced Porcine Splenic Damage via Activation of Nrf2/Keap1 Signal and Suppression of NFκb and STAT Signal
Not available
S-EPMC10094443 | biostudies-literature
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