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ProteomicsCharacterization of progressive denaturation and unfolding intermediates of proteins by fast cross-linking using di-ortho-phthalaldehyde
Chemical cross-linking of proteins coupled with mass spectrometry (CXMS) is widely used in protein structural analysis. In this study we develop a new class of non-hydrolyzable amine-selective di-ortho-phthalaldehyde (DOPA) cross-linkers, one of which is DOPA2. Cross-linking of proteins with DOPA2 i...
ORGANISM(S): Staphylococcus Aureus Bos Taurus 
2021-12-20 | PXD030552 |
ProteomicsAffinity-purification mass spectrometry on i) streptolysin O or C5a peptidase with human plasma or saliva; ii) human plasminogen with streptococcal proteins
In this project, we tried to use affinity-purification mass spectrometry (AP-MS) to study host-pathogen protein interaction, focusing initially on two major virulence factors of group A streptococcus (GAS), streptolysin O (SLO) and C5a peptidase (C5AP) with the immediate host microenvironment (human...
ORGANISM(S): Streptococcus pyogenes M1 GAS Homo sapiens (Human) Streptococcus pyogenes MGAS315 
2026-03-16 | PXD069402 | Pride
Group a streptococcus Protein-protein interaction Host-pathogen interaction Ap-ms 
Unknownd-Cycloserine augmentation of cognitive remediation in schizophrenia.
Not available
S-EPMC4547356 | biostudies-literature
MetabolomicsDistinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones

INTRODUCTION: Prostatitis is likely to occur in younger or middle-aged men, while prostate cancer is likely to occur in older men. Although amino acids and lipids as biomarkers of prostate cancer have been examined using prostate cancer cell lines/tissues, no previous studies hav...

2020-11-04 | MTBLS2028 | MetaboLights
TranscriptomicsSingle-cell RNA-seq for pGL2 and QC cells from the Arabidopsis thaliana root
To demonstrate our method of controlling for technical noise in single-cell RNA-seq experiments we manually collected single A. thaliana cells marked by the expression of green fluorescent protein (GFP) driven by either the GL2 or WOX5 promoters. Seven and six cells were collected from each cell typ...
ORGANISM(S): Arabidopsis thaliana 
2013-03-21 | E-MTAB-1499 | biostudies-arrayexpress
UnknownA programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system.
Not available
S-EPMC10769306 | biostudies-literature
UnknownCharacterization of the dual regulation by a c-di-GMP riboswitch Bc1 with a long expression platform from Bacillus thuringiensis.
Not available
S-EPMC11218506 | biostudies-literature
UnknownLicorice-Yuanhua Herbal Pair Induces Ileum Injuries Through Weakening Epithelial and Mucous Barrier Functions: Saponins, Flavonoids, and Di-Terpenes All Involved.
Not available
S-EPMC7378851 | biostudies-literature
ProteomicsStudy the effect of licorice-yuanhua combination on the gut mucosal barrier
licorice-yuanhua is one of the incompatible herbal pairs in the "Eighteen incompatible Medicaments" of traditional Chinese Medicine. In this study, Chemical compounds in licorice and yuanhua were used to treat the LS174T cells and iTRAQ labled proteomics study was conducted.
ORGANISM(S): Homo Sapiens 
2020-04-09 | PXD018456 |
UnknownCharacterization of protein unfolding by fast cross-linking mass spectrometry using di-ortho-phthalaldehyde cross-linkers.
Not available
S-EPMC8933431 | biostudies-literature
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