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UnknownA double-blinded, placebo-controlled randomized trial evaluating the efficacy and safety of Zhigancao Tang granules for treating HFpEF: study protocol for a randomized controlled trial.
Not available
S-EPMC8056488 | biostudies-literature
GenomicsTet and TDG Mediate DNA Demethylation Essential for MET in Somatic Cell Reprogramming
Tet-mediated DNA oxidation is a new type of epigenetic modification in mammals and its role in the regulation of cell fate transition remains poorly understood. Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet genes and examine their capability to be reprogrammed into iPS ...
ORGANISM(S): Mus musculus 
2014-02-19 | E-GEOD-52741 | biostudies-arrayexpress
UnknownFunctional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep.
Not available
S-EPMC5781304 | biostudies-literature
GenomicsRas-induced epigenetic inactivation of RRAD promotes glucose uptake in a human ovarian cancer model (RRBS-Seq]
Ras-related associated with diabetes (RRAD) is a small Ras-related GTPase that is frequently inactivated by DNA methylation of the CpG island in its promoter region in cancer tissues. However, the role of the methylation-induced RRAD inactivation in tumorigenesis remains unclear. In this study, the ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-55566 | biostudies-arrayexpress
GenomicsRas-induced epigenetic inactivation of RRAD promotes glucose uptake in a human ovarian cancer model
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-55568 | biostudies-arrayexpress
UnknownThe antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity.
Not available
S-EPMC3837159 | biostudies-literature
TranscriptomicsTranscription profiling by array of human SK-N-AS neuroblastoma xenograft tumor treated with anti-human IGF-IR monoclonal antibody (h10H5) to study the anti-tumour function of the antibody
The insulin-like growth factor (IGF) system consists of two ligands (IGF-I and IGF-II), which both signal through type I IGF receptor (IGF-IR) to stimulate proliferation and inhibit apoptosis, with activity contributing to malignant growth of many types of human cancers. We have developed a humanize...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11959 | biostudies-arrayexpress
UnknownNCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells.
Not available
S-EPMC9356278 | biostudies-literature
UnknownDeficiencies in corin and atrial natriuretic peptide-mediated signaling impair endochondral ossification in bone development.
Not available
S-EPMC11500007 | biostudies-literature
TranscriptomicsRas-induced epigenetic inactivation of RRAD promotes glucose uptake in a human ovarian cancer model [DGE-Seq]
Ras-related associated with diabetes (RRAD) is a small Ras-related GTPase that is frequently inactivated by DNA methylation of the CpG island in its promoter region in cancer tissues. However, the role of the methylation-induced RRAD inactivation in tumorigenesis remains unclear. In this study, the ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-55567 | biostudies-arrayexpress
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