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MetabolomicsAbsence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in Aeromonas veronii
Bacterial persisters are a small proportion of phenotypically heterogeneous variants with the transient capability to survive in high concentrations of antibiotics, causing recurrent infections in both human and aquatic animals. Transfer-messenger RNA (tmRNA), which was encoded by the ssrA ge...
2021-10-18 | MTBLS1182 | MetaboLights
TranscriptomicsRNA Polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA Polymerase II
Release of promoter-proximal paused RNA polymerase II (Pol II) during early elongation is a critical step in transcriptional regulation in metazoan cells. Paused Pol II release is thought to require the kinase activity of cyclin-dependent kinase 9 (CDK9) for the phosphorylation of DRB sensitivity-in...
ORGANISM(S): Homo sapiens 
2015-12-11 | E-GEOD-62171 | biostudies-arrayexpress
ProteomicsIdentification of a 144-amino-acid Scaffold Protein for Extracellular Vesicle Engineering
Extracellular vesicles (EVs) have emerged as promising drug-delivery vehicles. Genetic engineering of a membrane-bound, EV-sorting scaffold protein empowers these cell-borne nanosized vesicles by installing targeting moieties on the surface and enriching therapeutic cargo in the lumen. However, the ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD057965 | Pride
Expi293f-evs Lc-s/ms 
ProteomicsPlasma proteomic and metabolomic signatures of B-ALL patients during CAR-T cell therapy
The study aimed to assess plasma proteomic and metabolomic profiling in patients with B-ALL during humanized anti-CD19-CAR-T cell therapy
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040366 |
ProteomicsPlasma proteomic and metabolomic signatures of B-ALL patients during CAR-T cell therapy-2
The study aimed to assess plasma proteomic and metabolomic profiling in patients with B-ALL during humanized anti-CD19-CAR-T cell therapy
ORGANISM(S): Homo Sapiens 
2023-02-27 | PXD040411 |
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
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