Tango2 - OmicsDI

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Transcriptomics (42)
Unknown (37)
Genomics (6)
Proteomics (3)
Metabolomics (2)
Clinical (1)

Organisms

Saccharomyces cerevisiae (8)
Homo sapiens (8)
Rattus norvegicus (7)
Mus musculus (7)
Arabidopsis thaliana (3)
Bivalvia (3)
NEWT:479249 (3)
Chara australis (3)
Clavibacter michiganensis subsp. michiganensis NCPPB 382 (3)
Rapana venosa (3)
Agrobacterium fabrum str. C58 (3)
Beauveria bassiana ARSEF 2860 (3)
Physalis angulata (3)
Plasmodium (3)
Geobacillus sp. WSUCF1 (3)
Pomacea maculata (3)
Xylanibacter ruminicola (3)
bacterium BzS1 (3)
Enterococcus faecalis (2)
Candida albicans (2)
Mycoplasmoides pneumoniae (1)
Ostreococcus tauri (1)
Monodelphis domestica (1)
Halobacterium salinarum (1)
Schistosoma mansoni (1)
mixed sample (1)
Vibrio cholerae (1)
Plasmodium falciparum (1)
Pseudomonas aeruginosa (1)
Drosophila melanogaster (1)

Organisms

Homo sapiens (2)

Repository

biostudies-arrayexpress (45)
pride (3)
geo (2)
ENA (2)
MetaboLights (1)
MetabolomicsWorkbench (1)

Tissue

Brain (2)
Epithelial cell (2)
Cell culture (2)
Muscle (1)
Heart (1)
Liver (1)

Disease

Cataract (1)
Myopathy (1)
TANGO2-related metabolic encephalopathy and arrythmias (1)
Breast cancer (1)

Technology Type

Mass Spectrometry (4)
Data-dependent acquisition (2)
Mass spectrometry (1)
ESI (1)
Data-independent acquisition (1)
Bottom-up proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (2)
Non (1)
GenePix 4000A [Axon Instruments] (1)
Illumina Genome Analyzer II (1)
None (1)
Illumina (1)
NextSeq 2000 (1)
Illumina MiSeq (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 4000 (1)
Liquid Chromatography MS - positive - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2010 (13)
2025 (7)
2015 (4)
2007 (4)
2014 (3)
2011 (3)
2008 (3)
2024 (2)
2016 (2)
2012 (2)
2009 (2)
2023 (1)
2019 (1)
2013 (1)
2003 (1)
2021 (1)
2026 (1)

Metabolite Name

Adefovir Dipivoxil (Preveon, Hepsera) (1)
Indomethacin (Indocid, Indocin) (1)
MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
Toremifene Citrate (Fareston, Acapodene) (1)
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
(+)-Cycloolivil 4'-O-¦Â-D-glucopyranoside (1)
(+)-Fasciculic acid B (1)
(+)-Lyoniresinol 2¦Á-O-¦Â-D-glucopyranoside (1)
(-)-Medicocarpin;Medicarpin 3-O-glucoside (1)
(-)-Syringaresinol-4-O-¦Â-D-glucopyranoside (1)
(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(12Z)-9,10,11,14,15,16,17,18,19,20,21,22-Dodecahydro-5,8-ethenobenzo[20]annulene-2,4,6,24-tetrol (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,5S,8S,9S,10R,11R,12R,13S)-5,12,13-trihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,6R,11S,13S,14R,21R)-7,19,23-Triazahexacyclo[9.9.1.11,13.12,6.07,21.014,19]tricosane (1)

First Public Date

2025 (1)
2021 (1)

Study status

Recruiting (1)

Study type

Transcription profiling by array (31)
RNA-seq of coding RNA (6)
DNA-seq (3)
Unknown experiment type (1)
ChIP-seq (1)
Methylation profiling by array (1)
RNA-seq of coding RNA from single cells (1)
Observational patient registry (1)

Release Date

2010 (13)
2025 (10)
2023 (10)
2024 (6)
2016 (4)
2015 (4)
2008 (4)
2007 (4)
2019 (3)
2014 (3)
2011 (3)
2022 (3)
2017 (3)
2012 (2)
2009 (2)
2026 (2)
2021 (2)
2020 (2)
2013 (1)
2003 (1)

Lab affiliation

Centre for Medical Research, The University of Western Australia, QEII Medical Centre, Nedlands, Western Australia 6009, Australia (1)
ARC Centre of Excellence in Synthetic Biology, Macquarie University (1)
ARC Centre of Excellence in Synthetic Biology (1)

Location

United States (1)
Australia (1)

Keyword

Neglected Diseases (1)
Orphan Diseases (1)
Rare Disease Research (1)
Registries (1)
Batten Disease (1)
Mucolipidosis IV (1)
Undiagnosed (1)
Uncommon Disease (1)
Hypersomnia (1)
Marinesco-Sjogren Syndrome (1)
4p-/Wolf-Hirschhorn Syndrome (1)
Wiedermann-Steiner Syndrome (1)
Hemophagocytic Lymphohistiocytosis (HLH) (1)
Behcet’s Disease (1)
Jansen metaphyseal chondrodysplasia (1)
Chronic recurrent multifocal osteomyelitis (CRMO) (1)
Hereditary Sensory and Autonomic Neuropathy (1)
Nephropathic infantile cystinosis (1)
Ocular cystinosis (1)
Spinal Bulbar Muscular Atrophy (SBMA) (1)
Mucolipidosis (1)
Mitochondrial aminoacyl-tRNA synthetases (Mt-aaRS Disorders) (1)
Shine Syndrome (1)
Intestinal Bromhidrosis Syndrome (1)
Autosomal recessive extra oral halitosis (1)
CACNA1H mutation (1)
Dimethylglycine dehydrogenase deficiency (1)

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Lipidomics of Tango2 Deficient and Wildtype Zebrafish Muscle Tissue

Not available

ORGANISM(S): Danio rerio

ST002398 | MetabolomicsWorkbench

TANGO2 binds crystallin alpha B and its loss causes desminopathy

Mutations in the TANGO2 gene cause an autosomal recessive disorder characterised by developmental delay, stress-induced episodic rhabdomyolysis, and cardiac arrhythmias along with severe metabolic crises. Although TANGO2 mutations result in a well characterised disease pathology, the function of TAN...

ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human)

2025-04-22 | PXD056037 | Pride

Mitochondrial dysfunction associated with TANGO2 deficiency.

Not available

S-EPMC8866466 | biostudies-literature

TANGO2 binds crystallin alpha B and its loss causes desminopathy

PRJNA1157732 | ENA

TANGO2 binds crystallin alpha B and its loss causes desminopathy

BioID experiment looking at interactors of the protein cryab with/without presence of TANGO2

ORGANISM(S): Homo sapiens (Human)

2025-06-16 | PXD055705 | Pride

Tango2 Mitochondria Desminopathy

Reduction of charged glycoconjugates in TANGO2 KO mouse brain

The transport and Golgi organization 2 (TANGO2) gene has been identified to cause a rare recessive genetic disorder known as TANGO2-deficiency disorder (TDD). TDD is a multisystemic disorder that can affect different organs including the brain, heart, and muscles, presenting as recurrent metabolic c...

ORGANISM(S): Mus musculus (Mouse)

2026-02-10 | PXD068411 | Pride

Tango2 Mouse Glycomics Dda

Intrinsic and extrinsic regulation of rhabdomyolysis susceptibility by Tango2.

Not available

S-EPMC10499024 | biostudies-literature

TANGO2 binds crystallin alpha B and its loss causes desminopathy

ORGANISM(S): Homo sapiens

2025-04-21 | GSE276499 | GEO

TANGO2 is an acyl-CoA binding protein.

Not available

S-EPMC11867700 | biostudies-literature

TANGO2 binds crystallin alpha B and its loss causes desminopathy.

Not available

S-EPMC12144310 | biostudies-literature

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92 Results

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