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TranscriptomicsmRNA expression of 131 cancer cell lines
131 human cancer cell lines' mRNA expression profiles have been characterized. Keywords: Cell Line Comparison mRNA samples obtained from 131 human cancer cell lines were hybridized to Agilent Human 3.0 A1 arrays and gene expression (mlratio) was measured relative to a common reference RNA pool (Hum...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13598 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of human prefrontal cortex brain tissues
Dissecting the shared etiology of different diseases could benefit from a systematic search for associated molecules and their interactions. We investigated genome-wide disruptions in the co-regulation of genes in two neurodegenerative diseases, Alzheimer's or Huntington's disease (AD or HD), using ...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-33000 | biostudies-arrayexpress
TranscriptomicsObesity study in transgenic and knockout animals
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-12000 | biostudies-arrayexpress
TranscriptomicsGas7 male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11996 | biostudies-arrayexpress
TranscriptomicsGpx3 male transgenic liver expression vs B6/DBA male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11997 | biostudies-arrayexpress
TranscriptomicsGyk female heterozygous liver expression vs C57Bl/6J female wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11998 | biostudies-arrayexpress
TranscriptomicsLactb male transgenic liver expression vs FVB male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11999 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (CR)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44768 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (PFC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44770 | biostudies-arrayexpress
TranscriptomicsMulti-tissue gene expression profiles of human brain (VC)
The genetics of complex disease produce alterations in molecular interactions of cellular pathways which collective effect may become clear through the organized structure of molecular networks. To characterize molecular systems associated with late-onset Alzheimer´s disease (LOAD), we constructed g...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-44771 | biostudies-arrayexpress
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