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Cdk5i peptide treatment in aged Tau P301S mice
Abundance of tRNA fragments in Tau-RNA complexes from Tau-mutant PS19 (human P301S Tau transgenic) mice hippocampus
Abnormally accumulated tau protein aggregates are one of the hallmarks of dementia, including Alzheimer’s disease (AD), and are believed to play a critical role in neurodegeneration. In order to investigate proteomic alteration driven by tau aggregates, we implemented quantitative proteomics to anal...
ORGANISM(S): Mus Musculus (mouse) 
Tau-P301S sorted neurons and astrocytes
CNS cell-type specific gene profiling of aging P301S tau transgenic mice
P301S Mutant Tau-Driven Zebrafish Platform Enables Systematic Identification of Pharmacological GSK3β Inhibitors with Anti-Neurodegenerative Efficacy
Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy
LncRNA/mRNA sequencing analysis on cerebral cortex of P301S mutant Tau transgenic mice (PS19).
To investigate the effects of Cdk5i peptide treatment on gene expression in cortical neurons that isolated from aged Tau P301S mice
ORGANISM(S): Mus musculus 
2023-03-27 | GSE222327 | GEO
We report the binding between tRNA fragments and Phosphorylated Tau pS396 from the hippocampus of WT controls and Tau-mutant PS19 (human P301S Tau transgenic) mice. We show tRNA fragments abundance in Tau-RNA complexes changes between the two groups. Specific tRNA fragment in the results of Real Tim...
ORGANISM(S): Mus musculus 
2025-05-14 | GSE297027 | GEO
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