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TranscriptomicsExpression data in PD-L1 positive and PD-L1 negative human melanoma samples
Blocking the PD-1/PD-L1 immunosuppressive pathway has shown promise in the treatment of certain cancers including melanoma. This study investigates differences in the gene expression profiles of human melanomas that do or do not display the immunosuppressive protein PD-L1. Further understanding of g...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-65041 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53026 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [DREAM-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53025 | biostudies-arrayexpress
UnknownSafety and Clinical Activity of the Programmed Death-Ligand 1 Inhibitor Durvalumab in Combination With Poly (ADP-Ribose) Polymerase Inhibitor Olaparib or Vascular Endothelial Growth Factor Receptor 1-3 Inhibitor Cediranib in Women's Cancers: A Dose-Escalation, Phase I Study.
Not available
S-EPMC5493052 | biostudies-literature
TranscriptomicsGene expression of SUM159 breast cancer cell line expressing microRNA--203
Determine the effect of miR-203 expression on the global mRNA expression in mesenchymal breast cancer cell line. Generate control (pBabe puro) and miR-203 (pBabe puro miR-203) cells using retroviral transduction and puromycin selections. Extract total RNA using Trizol.
ORGANISM(S): Homo sapiens 
2013-09-23 | E-GEOD-50697 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [ChIP-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53023 | biostudies-arrayexpress
UnknownSurvival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.
Not available
S-EPMC4811023 | biostudies-literature
TranscriptomicsExpression data in human renal cell carcinoma samples from patients who did or did not respond to anti-PD-1 (Nivolumab) immunotherapy
Pre-treatment tumor expression of PD-L1 has been shown to correlate with favorable clinical outcomes following PD-1 blocking therapies. However, the majority of patients with PD-L1+ tumors do not respond to treatment. With the goal of obtaining insights into the mechanisms underlying the response to...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-67501 | biostudies-arrayexpress
UnknownFunctionalization of Pentaphosphorus Cations by Complexation.
Not available
S-EPMC6916545 | biostudies-literature
UnknownIn Situ N-Glycosylation Signatures of Epithelial Ovarian Cancer Tissue as Defined by MALDI Mass Spectrometry Imaging.
Not available
S-EPMC8870006 | biostudies-literature
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