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E.coli ATCC 25922 was overnight grown in 10 ml LB and passaged for 3 h with 1:50 dilution in fresh LB. Treated with tavaborole alone (80 μg/ml, labeled ‘A’) or tavaborole plus amikacin (80 μg/ml +40 μg/ml, labeled ‘AK’) for 6 h, cells were washed in PBS and harvested by centrifugation at 4,000 g, 8 ...
ORGANISM(S): Escherichia coli 
2023-03-10 | PXD033907 | Pride
On the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole
Genomics
Repurposing tavaborole to target beta-lactamases and leucyl-tRNA synthetases in drug-resistant Gram-negative bacteria
We presented the pharmacodynamic relationship between benzoxaborole concentrations and Candida albians blastoconidial population dynamics. Bis(benzoxaborole) analogue (2) and Tavaborole (ref.) showed comparable moderate effects against C. albicans (time-kill kinetic assays). Benzoxaboroles inhibited...
ORGANISM(S): Candida albicans 
2026-04-30 | GSE296032 | GEO
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