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TranscriptomicsTranscription profiling of human hepatitis PBMC C patients treated with Peg-interferon alfa-2b plus ribavirin during the first 10 weeks of treatment
Study of PBMC gene expression during the first 10 weeks of therapy with Pegylated-interferon-alfa2b (PegIntronTM) and ribavirin (administered by weight) in HCV patients. This study compared the kinetics of gene expression during the first 10 weeks of therapy with Pegylated-interferon-alfa2b (PegIntr...
ORGANISM(S): Homo sapiens 
2009-05-03 | E-GEOD-11342 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human A549 cell line treated with type I and II interferons vs. controls
Type I and type II interferons (IFNs) bind to different cell surface receptors but activate overlapping signal transduction pathways. We examined the effects of a type I IFN (IFN-acon1) and a type II iFN (IFN-g1b) on gene experession in A549 cells and demonstrate that there is a common set of genes ...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-5542 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hepatitis C patients - responders and non-responders to antiviral therapies peg interferon and ribavirin against hepatitis C
Time series of gene expression arrays before and during treatment of Hepatitis C; days 0, 1, 2, 7, 14 and 28 for 69 participants (IDs 1 through 69 are used). Treating chronic hepatitis C using peginterferon alpha and ribavirin leads to sustained clearance of virus and clinical improvement in approxi...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-7123 | biostudies-arrayexpress
GenomicThe Collaborative Study on the Genetics of Alcoholism (COGA)

COGA is a family study of alcoholism, in which the subjects have been drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), a large, ongoing family-based study that includes subjects from seven sites around the US. COGA has gathered detailed, standardized data on study particip...

phs000763 | dbGaP
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