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TranscriptomicsEzh2 maintains proliferation, transcriptional integrity, and the timing of late differentiation during mouse retina development
We investigated the gene expression profile changes after Ezh2 conditional knockout in the mouse retina at E16.5. Loss of Ezh2 leads to up-regulation of PRC2 targeted genes including cell cycle regulators and multiple genes which are not normally expressed in the retina, including many Hox genes. Lo...
ORGANISM(S): Mus musculus 
2015-07-14 | E-GEOD-65082 | biostudies-arrayexpress
MetabolomicsComparative Analyses of Metabolomic Fingerprints and Cytotoxic Activities of Soft Corals from the Colombian Caribbean
Soft corals (Cnidaria, Anthozoa, Octocorallia) are a diverse group of marine invertebrates that inhabit various marine environments in tropical and subtropical areas. Several species are recognized as prolific sources of compounds with a wide array of biological activities. Recent advances in analyt...
2018-11-08 | MTBLS777 | MetaboLights
TranscriptomicsMicL, a new ?E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein
In enteric bacteria, the transcription factor ?E maintains membrane homeostasis by inducing expression of proteins involved in membrane repair and of two small, regulatory RNAs (sRNAs) that downregulate synthesis of abundant membrane porins. Here, we describe the discovery of a third ?E-dependent sR...
ORGANISM(S): Escherichia coli 
2014-07-17 | E-GEOD-58637 | biostudies-arrayexpress
UnknownAssociation of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
Not available
S-EPMC9673026 | biostudies-literature
UnknownCommon, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.
Not available
S-EPMC8661833 | biostudies-literature
UnknownThe genetic architecture of the human cerebral cortex.
Not available
S-EPMC7295264 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
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