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Germline mutation of BRCA2 increases the lifetime risk of developing prostate cancer (PCa) by over 700%. BRCA2-mutant PCa have poorer prognosis than sporadic PCa, with rapid development of metastatic, castrate-resistant prostate cancer (mCRPC) and 5-year cancer-specific survival rates of ~50-60%1-4....
single nucleotide variant calls from somatic sniper, vcf format. input for subclonal reconstruction
Aligned sequence data from 14 Prostate cancer samples with BRCA2 mutations
single nucleotide variant calls from somatic sniper, vcf format
structural variant calls from Delly, vcf format
Raw Array data from the CPCGene BRCA study
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