Sort   by:  
 Page size 
GenomicsHigh-throughput pyrosequencing of forum domains termini (FT) isolated and amplified from human HEK293T cells
Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Mostly forum domains are of 50-200 kb in length, although larger domains, up to 500 - 700 kb, are also observed. We performed a genome-wide mapping of forum ...
ORGANISM(S): Homo sapiens 
2013-03-31 | E-GEOD-35065 | biostudies-arrayexpress
TranscriptomicsHot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation [DSBs]
Eukaryotic chromosomes are subjected to spontaneous fragmentation even under quick isolation of DNA in a solid phase by strong treatment with 0.1 M EDTA, 1% SDS and proteinase K (1 mg/ml). The long DNA fragments of excised chromosomal DNA were denoted as forum domains. Mostly forum domains are of 50...
ORGANISM(S): Homo sapiens 
2014-10-04 | E-GEOD-49302 | biostudies-arrayexpress
TranscriptomicsTiling path analysis of Drosophila Schneider 2 cultured cells to map forum domains
Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Mostly forum domains are of 50-200 kb in length, although larger domains, up to 500 - 700 kb, are also observed.

We performed a genome-wide mapping o...
ORGANISM(S): Drosophila melanogaster 
2010-11-01 | E-MEXP-2468 | biostudies-arrayexpress
GenomicsHot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation [rDNA units]
4C procedure was used for analysis of genomic contacts of rDNA units in HEK 293T cells. The primers for 4C were selected inside IGS. Our data indicate that mostly rDNA units exhibit close proximity with pericentromeric regions in different chromosomes. We also detected the contacts within a rDNA uni...
ORGANISM(S): Homo sapiens 
2014-10-04 | E-GEOD-49193 | biostudies-arrayexpress
Sort   by:  
 Page size