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TranscriptomicsTranscription profiling of Gata3 conditional knock out mice to investigate epidermis and hair follicle differentiation
Transcriptome analysis on Gata3 conditional knock out murine hair follicles. Background. The transcription factor Gata3 is critically involved in epidermis and hair follicle differentiation. Yet, little is known about how Gata3 co-ordinates stem cell lineage determination in skin, which processes ar...
ORGANISM(S): Mus musculus 
2007-01-01 | E-MEXP-634 | biostudies-arrayexpress
TranscriptomicsPretreatment microRNA expression impacting on epithelial to mesenchymal transition predicts intrinsic radiosensitivity in head and neck cancer cell lines and patients [miRNA-seq]
Purpose: Predominant causes of head and neck cancer recurrence after radiotherapy are rapid repopulation, hypoxia, fraction of cancer stem cells and intrinsic radioresistance. Currently, intrinsic radioresistance can only be assessed by ex-vivo colony assays. Besides being time-consuming, colony ass...
ORGANISM(S): Homo sapiens 
2016-03-23 | E-GEOD-79493 | biostudies-arrayexpress
GenomicsCopy number profiling of primary samples and cell lines of retinoblastoma
Illumina SNP-arrays for matching retinoblastoma-blood pairs and retinoblastoma cell lines.
EGAD00010000908 | EGA
GenomicsCopy number profiling of primary samples and cell lines of retinoblastoma
While RB1 loss initiates retinoblastoma development, additional somatic copy number alterations (SCNAs) can drive tumor progression. Although SCNAs have been identified with good concordance between studies at a cytoband resolution, accurate identification of single genes for all recurrent SCNAs is ...
EGAS00001001715 | EGA
GenomicsThe Dutch retinoblastoma research team from the VU University medical center
Data Access Committee EGAC00001000431
EGAC00001000431 | EGA
Genomicsena-DATASET-VUMC-CCA-03-02-2016-12:25:24:488-68 - samples
Paired-end whole exome sequenncing (Illumina) of primary enucleated retinoblastoma and matching lymphocyte DNA was performed to find somatic alterations that are related to oncogenesis.
EGAD00001001909 | EGA
GenomicsWhole exome sequencing on primary retinoblastoma tissues and matching lymphocyte DNA.
Retinoblastoma is a rare childhood cancer initiated by RB1 mutation or MYCN amplification, while additional alterations may be required for tumor development. However, the view on single nucleotide variants is very limited. To better understand oncogenesis, we determined the genomic landscape of ret...
EGAS00001001690 | EGA
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