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GenomicsNucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development
During differentiation of embryonic stem cells, chromatin reorganizes to establish cell type specific expression programs. Here, we have dissected the linkages between DNA methylation (5mC), hydroxymethylation (5hmC), nucleosome repositioning and binding of the transcription factor CTCF during this ...
ORGANISM(S): Mus musculus 
2014-05-07 | E-GEOD-56938 | biostudies-arrayexpress
GenomicsGenome-wide nucleosome positioning during embryonic stem cell development [ChIP-Seq]
We determined genome-wide nucleosome occupancy in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell type and protein specific binding preferences of transcription fact...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-40951 | biostudies-arrayexpress
GenomicsGenome-wide nucleosome positioning during embryonic stem cell development [MNase-Seq]
We determined genome-wide nucleosome occupancy in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell type and protein specific binding preferences of transcription fact...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-40910 | biostudies-arrayexpress
TranscriptomicsGenome-wide nucleosome positioning during embryonic stem cell development [RNA-Seq]
We determined genome-wide nucleosome occupancy in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell type and protein specific binding preferences of transcription fact...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-40948 | biostudies-arrayexpress
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