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ProteomicsTRB-mediated epigenetic gene regulation is controlled by distinct regulatory complexes utilizing specialized TRB paralogs
Epigenetic regulators shape chromatin landscapes, allowing cells to express distinct gene sets depending on cell-type, developmental stage or environmental cues. These regulatory complexes rely on interactions with sequence-specific DNA binding proteins, such as the small family of TELOMERE REPEAT B...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-13 | PXD069673 | Pride
Polycomb repressive complex 2 (prc2) Telomere repeat binding factors (trbs) 
GenomicsTRB and PRC2
Telobox cis-elements recruit CLF-PRC2 for H3K27me3 deposition via TELOMERE REPEAT BINDING FACTORs (TRBs) in Arabidopsis
PRJEB19936 | ENA
ProteomicsArabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14
Arabidopsis telomeric repeat binding factors (TRBs) can bind telomeric DNA sequences to protect telomeres from degradation. TRBs can also recruit Polycomb Repressive Complex 2 (PRC2) to deposit tri-methylation of H3 lysine 27 (H3K27me3) over certain target loci. Here, we demonstrate that TRBs also a...
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2023-02-22 | MSV000091349 | MassIVE
GenomicsTRB1-2-3-ChIP-seq-and-RNA-seq
Despite their genetic redundancy TRB genes in Arabidopsis show signs of specialization
PRJEB63124 | ENA
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