Sort   by:  
 Page size 
MetabolomicsMetabolome variability for two Mediterranean sponge species of the genus Haliclona: specificity, time, and space

INTRODUCTION: The study of natural variation of metabolites brings valuable information on the physiological state of the organisms as well as their phenotypic traits. In marine organisms, metabolome variability has mostly been addressed through targeted studies on metabolites of...

2021-10-27 | MTBLS638 | MetaboLights
MetabolomicsPlant-to-plant variability in root metabolite profiles of 19 Arabidopsis thaliana accessions is substance-class dependent
Natural variation of secondary metabolism between different accessions of Arabidopsis thaliana has been studied extensively. In this study, we extended the natural variation approach by including biological variability and analyzed root metabolic patterns as well as their variability between plants ...
2022-11-18 | MTBLS338 | MetaboLights
MetabolomicsMetabolic plasticity confers increased resilience to climate variability in temperate compared to tropical lizards

Patterns in functional diversity of organisms at large spatial scales can provide insight into possible responses to future climate change, but it remains a challenge to link large-scale patterns at the organismal level to their underlying physiological mechanisms. The climate variability hypothe...

2022-01-20 | MTBLS3627 | MetaboLights
MetabolomicsIndividual variability in human blood metabolites identifies age-related differences (30 persons, RBC data)
Metabolites present in human blood document individual physiological states influenced by genetic, epigenetic, and life-style factors. Using high-resolution liquid chromatography-mass spectrometry (LC-MS), we performed non-targeted, quantitative metabolomics analysis in blood of 15 young (29±4 yr) a...
2016-03-10 | MTBLS267 | MetaboLights
MetabolomicsIndividual variability in human blood metabolites identifies age-related differences (30 persons, plasma data)
Metabolites present in human blood document individual physiological states influenced by genetic, epigenetic, and life-style factors. Using high-resolution liquid chromatography-mass spectrometry (LC-MS), we performed non-targeted, quantitative metabolomics analysis in blood of 15 young (29±4 yr) a...
2016-03-10 | MTBLS266 | MetaboLights
MetabolomicsIndividual variability in human blood metabolites identifies age-related differences (30 persons, whole blood data)
Metabolites present in human blood document individual physiological states influenced by genetic, epigenetic, and lifestyle factors. Using high-resolution liquid chromatography-mass spectrometry (LC-MS), we performed nontargeted, quantitative metabolomics analysis in blood of 15 young (29 ± 4 y of ...
2016-03-10 | MTBLS265 | MetaboLights
MetabolomicsGlycaemic variability identified as a critical determinant of myocyte dysfunction and risk for myocardial injury in preclinical models of diabetes
Heart disease is the leading cause of morbidity and mortality in individuals with diabetes, due largely to risks associated with ischaemic injuries such as myocardial infarction (MI). We use human population genetic data to demonstrate that current biomarkers of hyperglycaemia do not account for ris...
2026-02-06 | MTBLS11411 | MetaboLights
MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Interspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS944 | MetaboLights
MetabolomicsIndividual variability in human blood metabolites identifies age-related differences - constant blood metabolite levels during 24h in 4 individuals
Metabolites present in human blood document individual physiological states influenced by genetic, epigenetic, and lifestyle factors. Using high-resolution liquid chromatography-mass spectrometry (LC-MS), we performed nontargeted, quantitative metabolomics analysis in blood of 15 young (29 ± 4 y of ...
2016-03-10 | MTBLS264 | MetaboLights
MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Intraspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS943 | MetaboLights
Sort   by:  
 Page size