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TranscriptomicsGenetic characterization of tumor-stage mycosis fungoides
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18098 | biostudies-arrayexpress
TranscriptomicsOncogenomic analysis of mycosis fungoides reveals major differences with Sézary syndrome
Mycosis fungoides (MF), the most common cutaneous T-cell lymphoma (CTCL), is a malignancy of mature, skin-homing T cells. Sézary syndrome (Sz) is often considered to represent a leukemic phase of MF. In this study the pattern of numerical chromosomal alterations in MF tumor samples was defined usin...
ORGANISM(S): Homo sapiens 
2008-09-29 | E-GEOD-12902 | biostudies-arrayexpress
TranscriptomicsNovel and highly recurrent chromosomal alterations in Sézary syndrome
This study was designed to identify highly recurrent genetic alterations typical of Sézary syndrome (Sz), an aggressive cutaneous T-cell lymphoma/leukemia, possibly revealing pathogenetic mechanisms and novel therapeutic targets. High-resolution array-based comparative genomic hybridization was don...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16384 | biostudies-arrayexpress
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