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ProteomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
Acute myeloid leukemia (AML) is an aggressive hematological malignancy arising from hematopoietic stem and progenitor cells (HSPCs). Current treatments often fail to eradicate AML, therefore, new therapeutic strategies are essential. Here, we reveal that RNA Terminal-Uridylyl-Transferase-Enzymes 4 a...
ORGANISM(S): Homo sapiens (Human) 
2026-06-24 | PXD077084 | Pride
Aml Terminal uridylyl-transferases Hspc 
GenomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
PRJNA1447503 | ENA
UnknownA Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases.
Not available
S-EPMC5485530 | biostudies-literature
UnknownEvolution of miRNA Tailing by 3' Terminal Uridylyl Transferases in Metazoa.
Not available
S-EPMC5509036 | biostudies-literature
GenomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
PRJNA1371002 | ENA
GenomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [SLAM-Seq]
RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [SLAM-Seq]
PRJNA1449483 | ENA
GenomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [RNA-seq]
RNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis [RNA-seq]
PRJNA1450008 | ENA
UnknownDual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases.
Not available
S-EPMC1976215 | biostudies-literature
TranscriptomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
Acute myeloid leukemia (AML) is an aggressive hematological malignancy arising from blood-forming hematopoietic stem and progenitor cells (HSPCs). Current therapies often fail to eradicate AML, therefore, identification of novel therapeutic targets is essential. Here, we reveal Terminal Uridylyl Tra...
ORGANISM(S): Mus musculus 
2026-07-17 | GSE311841 | GEO
GenomicsRNA Terminal Uridylyl-Transferases Are Druggable Vulnerabilities in AML, but are Dispensable for Normal Hematopoiesis
Acute myeloid leukemia (AML) is an aggressive hematological malignancy arising from hematopoietic stem and progenitor cells (HSPCs). Current treatments often fail to eradicate AML; therefore, new therapeutic strategies are essential. Here, we reveal that RNA Terminal-Uridylyl-Transferase-Enzymes 4 a...
ORGANISM(S): Mus musculus 
2026-06-24 | GSE326857 | GEO
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