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TranscriptomicsMicroRNA profiling of human hepatocellular carcinoma samples shows miR-221 overexpression contributes to liver tumorigenesis
We profiled miRNA expression in tissue samples (104 HCC, 90 adjacent cirrhotic livers, 21 normal livers) as well as in 35 HCC cell lines. A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93,miR-96, and let-7c) was linked to disease progression from normal liver through cirrh...
ORGANISM(S): Homo sapiens 
2009-12-08 | E-TABM-866 | biostudies-arrayexpress
TranscriptomicsIGR_BREAST_EXON_AGILENT_STUDY_FA
We profiled breast cancer samples with exon arrays (244K Agilent Human exon) in order to identify exons associated with higher risk of relapse. This set contain 178 single dual color of samples (biopsies) versus normal breast reference (Normal breast Clontech) , 5 dye-swap (10 hybridizations) and...
ORGANISM(S): Homo sapiens 
2013-05-07 | E-MTAB-1389 | biostudies-arrayexpress
GenomicsT-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism.
β-catenin signaling can be both a physiological and an oncogenic pathway in the liver. It controls compartmentalized gene expression, allowing the liver to ensure its essential metabolic function. It is activated by mutations in 20 to 40% of hepatocellular carcinomas with specific metabolic features...
ORGANISM(S): Mus musculus 
2014-01-18 | E-GEOD-35213 | biostudies-arrayexpress
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