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UnknownTrk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.
Not available
S-EPMC5638802 | biostudies-literature
UnknownDeregulation of CLTC interacts with TFG, facilitating osteosarcoma via the TGF-beta and AKT/mTOR signaling pathways.
Not available
S-EPMC8214859 | biostudies-literature
UnknownTRK-fused Gene Protein Localization Is Prominent in Serotonergic and Noradrenergic Cell Groups, and Some Lower Motor Neurons in the Corticospinal Tract of the Rat Brainstem.
Not available
S-EPMC6066645 | biostudies-literature
UnknownTFG-β Nuclear Staining as a Potential Relapse Risk Factor in Early-Stage Non-Small-Cell Lung Cancer.
Not available
S-EPMC9694009 | biostudies-literature
UnknownWnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway.
Not available
S-EPMC7726150 | biostudies-literature
TranscriptomicsFoxd1 expression identifies a distinct subset of hepatic stellate cells involved in liver fibrosis
Hepatic stellate cells (HSCs) are pericytes of the liver and are responsible for liver fibrosis and cirrhosis, which are end stages of chronic liver diseases. TFG-β activates HSCs leading to differentiation of myofibroblasts in the process of liver fibrosis. While heterogeneity of HSCs is appreciate...
ORGANISM(S): Mus musculus 
2025-06-17 | GSE270404 | GEO
UnknownTransforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis.
Not available
S-EPMC4521372 | biostudies-literature
TranscriptomicsTranscriptomic fingerprints of C. elegans exposed to citrate coated superparamagnetic iron oxide nanoparticles (C-SPIONs)
Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are currently being investigated for a range of biomedical applications. Their use have been related with different cytotoxic mechanisms including the generation of oxidative stress and the induction of metal detoxification pathways, among others. ...
ORGANISM(S): Caenorhabditis elegans 
2018-01-05 | GSE93187 | GEO
ProteomicsALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression
Anaplastic lymphoma kinase (ALK) fusion variants in non-small-cell-lung cancer (NSCLC) consist of numerous dimerising fusion partners, with the most common being EML4. Clinical data suggests that the degree of treatment benefit in response to ALK tyrosine kinase inhibitors (TKIs) differs among the v...
ORGANISM(S): Homo sapiens (Human) 
2023-02-16 | PXD035100 | Pride
Human Nsclcl Orbitrap fusion lumos 
UnknownIdentification of isoliquiritigenin as an activator that stimulates the enzymatic production of glycyrrhetinic acid monoglucuronide.
Not available
S-EPMC5624897 | biostudies-literature
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