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GenomicsRegulation of Mediator-dependent transcriptional activation of Pol II(G) through TFII
Pol II(G) is a novel form of RNA polymerase II that contains a tightly associated Gdown1 polypeptide. Whereas Pol II suffices for robust activator-dependent transcription in the absence of Mediator, Pol II(G) is highly dependent upon Mediator in a biochemically defined in vitro system. However, the ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-33128 | biostudies-arrayexpress
GenomicsFunctional association of Gdown1 with RNA Polymerase II in Human
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-32442 | biostudies-arrayexpress
GenomicsWhole Cell Extract
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-35882 | biostudies-arrayexpress
UnknownSuper elongation complex contains a TFIIF-related subcomplex.
Not available
S-EPMC4984678 | biostudies-literature
UnknownMolecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.
Not available
S-EPMC3066130 | biostudies-literature
UnknownRNA polymerase III-specific general transcription factor IIIC contains a heterodimer resembling TFIIF Rap30/Rap74.
Not available
S-EPMC3799434 | biostudies-literature
UnknownThe positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.
Not available
S-EPMC2483787 | biostudies-literature
GenomicsEffects of sumoylation-impairing mutation of TFIIF subunit Tfg1 on genome-wide RNA polymerase II (RNAPII) levels in budding yeast
Effects of sumoylation-impairing mutation of TFIIF subunit Tfg1 on genome-wide RNA polymerase II (RNAPII) levels in budding yeast
PRJNA704639 | ENA
UnknownMolecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF.
Not available
S-EPMC151334 | biostudies-literature
UnknownArchitecture of the RNA polymerase II-TFIIF complex revealed by cross-linking and mass spectrometry.
Not available
S-EPMC2810376 | biostudies-literature
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