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TranscriptomicsExpression data from wildtype and Tfr1 heart KO mice
We deleted Tfr1 in the heart to determine the role of Tfr1 in iron uptake in normal cardiac funciton We used microarrays to identify global gene changes associated with deletion of Tfr1 in skeletal muscle We isolated RNA from WT and Tfr1 KO hearts at both postnatal day 5 and postnatal day 10.RNA wa...
ORGANISM(S): Mus musculus 
2015-05-12 | E-GEOD-68745 | biostudies-arrayexpress
TranscriptomicsExpression data from wildtype and Tfr1 skeletal muscle KO mice
Tfr1 is important for iron uptake in red blood cells. We deleted Tfr1 in skeletal muscle to determine the role of Tfr1 in iron uptake in skeletal muscle. We used microarrays to identify global gene changes associated with deletion of Tfr1 in skeletal muscle We used skeletal muscle and liver from wil...
ORGANISM(S): Mus musculus 
2015-05-08 | E-GEOD-68675 | biostudies-arrayexpress
TranscriptomicsThe transferrin receptor is required for intestinal epithelial homeostasis
The role of Tfr1 in non-erythroid tissues remains elusive due to the embryonic lethality of the Tfr1 global knockout mouse model. To bypass this problem, we generated a mouse model in which Tfr1 was conditionally deleted in intestinal epithelial cells (IECs). These mice developed severe IEC disrup...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-68984 | biostudies-arrayexpress
ProteomicsProteins that interact with TfR1
Transferrin receptor 1 (TfR1), a widely expressed type II transmembrane glycoprotein located on the plasma membrane, is well known for its established role in cellular iron uptake. Nevertheless, emerging evidence implies that TfR1 exhibits previously unrecognized noncanonical functions. Herein, we d...
ORGANISM(S): Homo sapiens (Human) 
2025-07-08 | PXD063330 | Pride
Human cancer lc-msms 
ProteomicsLC-MS/MS analysis of Gd-IgA1 and secretary TfR1 cross-linked complex
The retention of galactose-deficient IgA1 (Gd-IgA1) in the glomerular mesangium is a hallmark of IgA nephropathy (IgAN). The immune complex formed by Gd-IgA1 binds to transferrin receptor 1 (TfR1) and deposits on mesangial cell, inducing cell proliferation, inflammatory response, matrix secretion, e...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD063709 | Pride
Galactose-deficient iga1 Transferrin receptor Iga nephropathy 
GenomicsTfR1 globally regulates transcription and alternative splicing
TfR1 globally regulates transcription and alternative splicing
PRJNA544112 | ENA
TranscriptomicsExpression data from wildtype and Tfr1 skeletal muscle KO mice
Tfr1 is important for iron uptake in red blood cells. We deleted Tfr1 in skeletal muscle to determine the role of Tfr1 in iron uptake in skeletal muscle. We used microarrays to identify global gene changes associated with deletion of Tfr1 in skeletal muscle
ORGANISM(S): Mus musculus 
2015-05-08 | GSE68675 | GEO
TranscriptomicsExpression data from wildtype and Tfr1 heart KO mice
We deleted Tfr1 in the heart to determine the role of Tfr1 in iron uptake in normal cardiac funciton We used microarrays to identify global gene changes associated with deletion of Tfr1 in skeletal muscle
ORGANISM(S): Mus musculus 
2015-05-12 | GSE68745 | GEO
GenomicsTfR1 extensively regulates the expression of genes associated with ion transport and immunity
TfR1 extensively regulates the expression of genes associated with ion transport and immunity
PRJNA533638 | ENA
GenomicsNuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation [Cut&Tag]
Nuclear translocation of TfR1 facilitating tumor progression via p53-mediated gene regulation [Cut&Tag]
PRJNA1129876 | ENA
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