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Microglial gene expression after TGFb1 treatment in vitro
Primary human bone marrow-derived mesenchymal stem cells (MSCs) were treated with recombinant human TGFb1 (10ng/ml) for different time points (1, 3, 7, 14, 24 hours)
ORGANISM(S): Homo sapiens 
Fibroblast-derived TGFb1 regulates skin repair and fibrosis
Effect of TGFb1 treatment and WISP1 overexpression on 4T1 breast cancer cells
In brief, PANC-1 cells stably transfected with a dominant negative HRAS(S17N) mutant, a constitutively active KRAS2(G12V) mutant, or mock transfected with an EGFP expression construct were treated with TGFB1 or left untreated, respectively. Three independent experiments each were analyzed in duplica...
ORGANISM(S): Homo sapiens 
MiRNA expression in a patient-derived CRC model after treatment with TGFB1
Transgenic (Tg) mice over-expressing TGFb1 in a lung-specific manner display airway inflammation and fibrosis, phenotypes relevant to human COPD and asthma. This model system provides a platform for identifying and validating genes/pathways involved in these disease pathogeneses. The TGFb1-Tg mice l...
ORGANISM(S): Mus musculus 
Targeting of the YAP/SMAD molecular circuit inhibits a TGFb1-induced myofibroblast phenotype
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