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Stem Cells and Metabolism Research Program and Dept. of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland; (1)
Plateforme Proteome, Univ. Bordeaux, Bordeaux, France (1)
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Core Facility for Mass Spectrometry and Proteomics, Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany (1)
Charles Perkins Centre, School of Medical Sciences, University of Sydney, Sydney, Australia. (1)

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Halobacterium rubrum strain:TGN-42-S1

Halobacterium rubrum strain:TGN-42-S1 Genome sequencing and assembly

PRJNA787370 | ENA

Anti-leukemic effect of TGN-1062, a novel CDK7 inhibitor, on AML-leukemic stem cells by targeting RNA modification and Mitochondrial metabolism

High expression of CDK7, a cell cycle regulator and transcriptional modulator, correlates with poor outcomes in acute myeloid leukemia (AML). We report that TGN-1062, a novel CDK7 inhibitor, exhibits significant antileukemic effects by inhibiting cell growth and inducing apoptosis in AML cell lines ...

ORGANISM(S): Homo sapiens

2024-11-24 | GSE282364 | GEO

GRIA1 regulates TGN export and secretion of Sonic hedgehog.

Not available

S-EPMC12858347 | biostudies-literature

Anti-leukemic effect of TGN-1062, a novel CDK7 inhibitor, on AML-leukemic stem cells by targeting RNA modification and Mitochondrial metabolism

PRJNA1188203 | ENA

The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.

Not available

S-EPMC5294781 | biostudies-literature

SOI1 encodes a novel, conserved protein that promotes TGN-endosomal cycling of Kex2p and other membrane proteins by modulating the function of two TGN localization signals.

Not available