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TranscriptomicsGenome wide STAT3 RNAi expression profiling data from Thp,Th0 and Th17 cells
STAT3 is an immidiate regulator of Th17 differentiation. STAT3 difieciency downmodulate Th17 specific genes and Th17 responses. Therefore, we intend to identify genome wide targets of STAT3. We used microarrays to profile gene expression of STAT3 regulated genes during Th17 polarization. Total RNA w...
ORGANISM(S): Homo sapiens 
2017-05-03 | E-GEOD-67185 | biostudies-arrayexpress
TranscriptomicsmiRNA-seq study between Th0 and Th17 cells
To explore the differences in miRNA profiles, naive CD4+CD62L+ helper T cells were sorted by magnetic cell sorting from spleens of female C57BL/6 mice and were induced to differentiate into Th1 or Th17 cells, then total RNA was extracted and miRNA-seq were conducted. The results showed that many mi...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-80834 | biostudies-arrayexpress
TranscriptomicsCombinatorial flexibility of cytokine during Human T helper cells differentiation
Transcriptional analysis of human T cells differentiated in 4 T Helper context ( Th0, Th1, Th2 and Th17) in the presence or not of Interferon alpha We analyzed the transcriptomic profiles of 4 human naives T cells diferentiated in Th0, Th1, Th2 and Th17 in the presence or not of Interferon Alpha. Mi...
ORGANISM(S): Homo sapiens 
2014-05-29 | E-GEOD-54627 | biostudies-arrayexpress
GenomicsPopulation ATAC-seq of in vitro polarized Th0 cells
Population ATAC-seq of in vitro polarized Th0 cells
PRJNA1259496 | ENA
Transcriptomicsin vitro differentiated Th0, Th17, and Tr1 cells
Gene expression profiling of in vitro differentiated murine Th cell subsets. Flow cytometrically sorted naive Th cells (CD4+ CD44- Foxp3-) were polyclonally stimulated in vitro for 3 days using 4 µg/ml plate-bound antibody to CD3 (145-2C11) and 2 µg/ml soluble antibody to CD28 (PV-1). Th0 cells we...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-56021 | biostudies-arrayexpress
GenomicsPopulation ATAC-seq of in vitro polarized Th0 cells
To understand the molecular programs driving T helper cell heterogeneity and fate, we profiled in vitro polarized Th0 using ATAC-seq. This data were generated as part of the timecourse experiment in GSE206607.
ORGANISM(S): Mus musculus 
2026-06-12 | GSE296490 | GEO
GenomicsGenome-wide binding of Ikaros in naive CD4+ T cells and Th0 at day1
Genome-wide binding of Ikaros in naive CD4+ T cells and Th0 at day1
PRJNA662892 | ENA
TranscriptomicsCompare gene expression profiles of Th0, Th1 and Th17
Transcriptome analysis to investigate the expression profile of Th0, Th1 and Th17.
ORGANISM(S): Mus musculus 
2022-09-08 | E-MTAB-10398 | biostudies-arrayexpress
Transcriptomicsin vitro differentiated Th0, Th17, and Tr1 cells
Gene expression profiling of in vitro differentiated murine Th cell subsets. Flow cytometrically sorted naive Th cells (CD4+ CD44- Foxp3-) were polyclonally stimulated in vitro for 3 days using 4 µg/ml plate-bound antibody to CD3 (145-2C11) and 2 µg/ml soluble antibody to CD28 (PV-1). Th0 cells were...
ORGANISM(S): Mus musculus 
2014-03-20 | GSE56021 | GEO
TranscriptomicsTranscription profiling of mouse spleen CD4+ CD44Low CD62LHigh cells stimulated with anti-CD3 or anti-CD28 in the presence or absence of hTGFb-1 and mouse IL-6
Mouse spleen CD4+CD44LowCD62LHigh cells were stimulated with 2ug/ml anti-CD3(eBioscience), 2ug/ml anti-CD28 (eBioscience) in the presence (Th17 condition) or absence (Th0 condition) of hTGFb-1 (1ng/ml eBioscience), mouse IL-6(10ng/ml eBioscience). Cells were collected after 24 hourÕs culture using R...
ORGANISM(S): Mus musculus 
2008-12-21 | E-TABM-583 | biostudies-arrayexpress
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