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TranscriptomicsDiscovery of genes regulated by the metastasis suppressor gene, RhoGDI2
A number of studies find that metastasis suppressor proteins, including RhoGDI2, may function in part though controlling expression of genes regulating metastasis (reviewed in Smith and Theodorescu, Nature Reviews Cancer, 2009, PMID: 19242414). To uncover systematically gene expression patterns depe...
ORGANISM(S): Homo sapiens 
2012-04-14 | E-GEOD-35014 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of 19 bladder cancers from the University of Virginia
Given the heterogeneity of disease evident from study of the presentation, histomorphology, disease course, and molecular lesions of bladder cancer, a cohort of 8 non-muscle invasive and 11 muscle invasive bladder cancers were profiled for gene expression using the Affymetrix HG-U133A platform. Unde...
ORGANISM(S): Homo sapiens 
2012-12-24 | E-GEOD-37317 | biostudies-arrayexpress
UnknownLong-term Outcomes from a Phase 2 Study of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer (SWOG S1314; NCT02177695).
Not available
S-EPMC10659139 | biostudies-literature
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [copy number variation]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64572 | biostudies-arrayexpress
TranscriptomicsThe UBC-40 Urothelial Bladder Cancer Cell Line Index [gene expression]
This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental diso...
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-64279 | biostudies-arrayexpress
TranscriptomicsHuman patient tumor-derived organoid characterization from bladder cancer patients that did not respond to chemotherapy
A total of 3 independently derived organoids were compared to patient tumor samples and patient normal samples to determine if the tumor-derived organoids represent the genomic landscape of the tumor from which they were derived.
ORGANISM(S): Homo sapiens 
2023-01-02 | E-MTAB-10353 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling in four human bladder cancer cell lines
To identify miRNA-target interactions that are important in bladder cancer metastasis, we profiled miRNA and mRNA expression in poorly metastatic cell lines T24 and LUC, and their metastatic derivatives FL4 and LUL2, respectively. We reasoned that miRNAs and genes that expressed differently between ...
ORGANISM(S): Homo sapiens 
2014-07-25 | E-MTAB-2611 | biostudies-arrayexpress
UnknownA community effort to assess and improve drug sensitivity prediction algorithms.
Not available
S-EPMC4547623 | biostudies-literature
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