Therapeutic antibodies

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Unknown (10527)
Genomics (909)
Transcriptomics (814)
Proteomics (317)
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Models (13)
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Methylation profiling (2)

Organisms

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unidentified (3)
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human nasopharyngeal metagenome (1)
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Organisms

Homo sapiens (286)
Mus musculus (258)
Rattus norvegicus (4)
Mammalia (2)
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Severe acute respiratory syndrome coronavirus 2 (2)
Saccharomyces cerevisiae (2)
Human respirovirus 3 (1)
Macaca (1)
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Cricetulus griseus (1)
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Macaca fascicularis (1)
Canis lupus familiaris (1)
mouse gut metagenome (1)
Streptococcus pyogenes (1)

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biostudies-arrayexpress (732)
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geo (356)
pride (144)
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Tissue

Cell culture (34)
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Blood cell (8)
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Cell suspension culture (4)
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Primary cell (3)
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T cell (2)
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B-cell lymphoma/leukemia 11B (1)
B-lymphocyte (1)
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Breast epithelium (1)
Cardiomyocyte cell line (1)
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RAW-264.7 cell (1)

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HPV positive (1)
Dermal neurofibroma (1)
Anaplastic large cell lymphoma has DiseaseStaging II (1)
Gliosarcoma (1)
"colon adenocarcinoma, acterial infection" (1)
Cirrhosis (1)
Coronary artery disease (1)
Normal (1)
Not Available (1)
Autism spectrum disorder (1)
B-cell acute lymphoblastic leukemia (1)
Bowel dysfunction (1)
Candidiasis (1)
Cardiovascular system disease (1)
Cervix carcinoma (1)
Chronic fatigue syndrome (1)

Technology Type

Mass Spectrometry (144)
Shotgun proteomics (56)
Bottom-up proteomics (33)
Affinity purification coupled with mass spectrometry proteomics (25)
Data-dependent acquisition (22)
Data-independent acquisition (20)
Mass spectrometry (13)
Gel-based experiment (9)
Top-down proteomics (9)
SWATH MS (8)
Chemical cross-linking coupled with mass spectrometry proteomics (4)
Immunopeptidomics (4)
Illumina HiSeq 2000 (3)
ILLUMINA, Illumina HiSeq 2500 (2)
NMR spectroscopy (2)
Illumina Oncoscan Array (1)
ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2500 (1)
Illumina MiSeq (1)
Fluorescence imaging (1)
Fluorescence intensity (1)
Mass spectrometry assay (1)
DiaPASEF (1)
Glycoproteomics (1)
MSE (1)
Mass spectrometry imaging (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (74)
NextSeq 500 (22)
NextSeq 2000 (14)
Illumina HiSeq 2500 (14)
Illumina NovaSeq X (11)
Illumina HiSeq 4000 (11)
NextSeq 550 (10)
Illumina HiSeq 2000 (7)
Qubit 4.0 Fluorometer/ Agilen 5300 Fragment Analyzer (3)
NextSeq 1000 (3)
10x Genomics Chromium Controller (3)
Illumina HiSeq 1500 (3)
10x Genomics Chromium (2)
DNBSEQ-G400 (2)
DNBSEQ-T7 (2)
Illumina MiSeq (2)
Illumina HiSeq 3000 (2)
Illumina HiSeq 2000 platform (1)
Illumina NextSeq2000 (2x100bp) (1)
Cellranger (1)
FACS BD Aria II & III (1)
CellRanger v2.1.0 (1)
Using NEBNext Ultra II DNA Library (1)
HISAT2, TOPHAT2 (1)
Lab Bench (1)
KAPA EvoPrep Kit (1)
Performed by Novogene; Illumina library preparation instrumentation (provider standard) (1)
Chromatin IP kit (1)
Immunomagnetic separation system (e.g., Miltenyi MACS separator), Tissue culture facilities (biosafety cabinet, CO₂ incubator) , Bench centrifuge (1)
Nanodrop 2000c spectrophotometer (1)

Publication Date

2025 (176)
2026 (172)
2024 (106)
2013 (105)
2015 (104)
2014 (90)
2023 (74)
2012 (74)
2016 (56)
2022 (54)
2021 (53)
2010 (52)
2020 (49)
2011 (41)
2017 (37)
2009 (29)
2019 (28)
2008 (25)
2018 (22)
2007 (12)
2006 (4)
2003 (2)
2005 (1)
2027 (1)

UNIPROT ID/AC

P02741 (4)
P05231 (4)
P08887 (4)
P08473 (1)

CHEBI ID

CHEBI:16359 (6)
CHEBI:15428 (6)
CHEBI:16755 (6)
CHEBI:78320 (5)
CHEBI:16525 (5)
CHEBI:15756 (5)
CHEBI:16414 (5)
CHEBI:17895 (5)
CHEBI:17295 (5)
CHEBI:16467 (5)
CHEBI:16919 (5)
CHEBI:30769 (5)
CHEBI:72665 (5)
CHEBI:15891 (5)
CHEBI:16393 (5)
CHEBI:15611 (5)
CHEBI:32816 (5)
CHEBI:16196 (5)
CHEBI:16857 (5)
CHEBI:17115 (5)
CHEBI:16643 (5)
CHEBI:18019 (5)
CHEBI:15603 (5)
CHEBI:17191 (5)
CHEBI:18050 (5)
CHEBI:17196 (5)
CHEBI:30805 (5)
CHEBI:28834 (5)
CHEBI:52217 (2)
CHEBI:64645 (1)

Metabolite Name

Isocitric acid (4)
Ornithine (4)
L-Lysine (4)
Cytosine (4)
L-Methionine (4)
Taurine (4)
Oleic acid (4)
Pyroglutamic acid (4)
L-Valine (4)
L-Arginine (4)
Uridine (4)
L-Phenylalanine (4)
Hydrogen phosphate (3)
Pyrrolidonecarboxylic acid (3)
Sorbitol (3)
Deoxyuridine (3)
Palmitoleic acid (3)
Gamma-Aminobutyric acid (3)
4,5-Dihydroorotic acid (3)
Isovaleric acid (3)
Ketoleucine (3)
Deoxycholic acid (3)
Indole (3)
Maleic acid (3)
Cholic acid (3)
Saccharopine (3)
Carnosine (3)
5-Hydroxylysine (3)
L-Proline (3)
L-Kynurenine (3)

First Public Date

2025 (143)
2024 (115)
2026 (102)
2023 (66)
2021 (41)
2020 (40)
2014 (38)
2022 (35)
2017 (25)
2015 (17)
2019 (15)
2016 (12)
2018 (9)
2013 (6)

Modelling Approach

Ordinary differential equation model (5)
Differential equation model (1)

Study status

Recruiting (3)
Completed (3)
Not provided (1)

Lab affiliation

Aarhus University Department of Biomedicine DK-8000 Aarhus (3)
Division of Medical Inflammation Research, Dept. Medical Biochemistry and Biophysics, Karolinska Institute, Sweden (3)
MRC PPU University of Dundee (3)
Molecular Leukemogenesis Group, German Cancer Research Center, Heidelberg, Germany Heidelberg University, Medical Faculty, Heidelberg, Germany, 6Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany (3)
Department of Biochemistry and Molecular Biology and the Biomedicine Discovery Institute; Monash University; Clayton 3800; Victoria; Australia (2)
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (2)
, Dana-Farber Cancer Institute, Harvard Medical School 360 Longwood Avenue Longwood Center, LC4117 Boston, MA 02215 (1)
1: Department of Molecular Biology, Division of Chemistry andBioanalytics, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria 2: Christian Doppler Laboratory for Innovative Tools for Biosimilar Characterization, University of Salzburg, Hellbrunner Strasse 34, 5020 Salzburg, Austria (1)
1CHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada 2 Department of Pathology and cellular biology, Faculty of Medicine, Universite de Montreal, QC H3T 1J4, Canada (1)
Aix-Marseille univ, CNRS, Inserm, Institut Paoli-Calmettes, CRCM, Marseille Protéomique (1)
Assistant Professor, Gene Expression & Regulation Program, Wistar Institute Cancer Center, Philadelphia PA, USA (1)
Associate Director of Analytical Services, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA (1)
Associate Professor, University of Washington (1)
Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland (1)
Beijing University of Chinese Medicine, School of Traditional Chinese Medicine, Attending Physician, Assistant Researcher (1)
Biological Mass Spectrometry Lab, Department of Translational Medicine, University of Piemonte Orientale (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics,Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, Utrecht 3584 CH, The Netherlands Netherlands Proteomics Center, Padualaan 8, Utrecht 3584 CH, the Netherlands (1)
COI-NDM (University of Oxford) (1)
Calico Life Sciences (1)
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Cambridge, UK (1)
Cancer Research Center, School of Medicine, Xiamen University (1)
Cancer Research Institute, Xiangya Basic Medical College, Central South University, No. 110 Xiangya Road, Kaifu District, Changsha City, Hunan Province (1)
Cancer Sciences, Faculty of Medicine, University of Southampton, UK (1)
Cedars-Sinai Medical Center (1)
Center for Neuroscience and Cell Biology – University of Coimbra (1)
Center of experimental therapeutics Department of oncology UNIL CHUV Ludwig Institute for Cancer Research Lausanne Centre de recherche Agora Rue du Bugnon 25A CH-1005 Lausanne (1)
Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)

Keyword

Antibodies (2)
Antibodies, Monoclonal (2)
Bevacizumab (2)
PD-1 monoclonal antibody (1)
PMMR/MSS (1)
Circulating cell free DNA (1)
Treatment efficiency (1)
NGS (1)
MFOLFOX6 (1)
Circulating tumor cells (1)
Sonovue (1)
Microbubbles (1)
Sonoporation (1)
Hepatic metastases of colorectal cancer (1)
Cetuximab (1)

IsPrivate

False (6)

Submitter Keywords

Not Peer Reviewed (1)

Classification

viruses (3)
bacteria (1)

Modification

-17.026549 (1)
-18.010565 (1)
15.994915 (1)
42.010565 (1)
57.021464 (1)
79.966331 (1)

Study type

Transcription profiling by array (303)
ChIP-seq (163)
RNA-seq of coding RNA (79)
RNA-seq of coding RNA from single cells (53)
Proteomic profiling by array (34)
Other (13)
CUT&RUN (13)
Methylation profiling by array (11)
ChIP-chip by tiling array (10)
Comparative genomic hybridization by array (6)
RNA-seq of total RNA (6)
Unknown experiment type (4)
RIP-seq (4)
Methylation profiling by high throughput sequencing (4)
Genotyping by array (3)
Hi-C (3)
DNA-seq (3)
RNA-seq of non coding RNA (3)
Human - One-color microarray (2)
ATAC-seq (2)
CUT&Tag (1)
Transcription profiling by SAGE (1)
Human - Methylation microarray (1)
Human - High-throughput sequencing (1)
Cell line - One-color microarray (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
ChIP-chip by array (1)
Antigen profiling (1)

Release Date

2022 (1372)
2021 (1325)
2023 (1131)
2025 (1052)
2020 (970)
2024 (912)
2019 (674)
2018 (584)
2016 (519)
2017 (518)
2015 (490)
2014 (385)
2013 (299)
2012 (232)
2026 (217)
2011 (156)
2010 (125)
2009 (106)
2008 (65)
2007 (40)
2006 (35)
2005 (23)
2003 (5)
2002 (4)
1998 (4)
2000 (3)
2004 (2)
2001 (2)
1999 (2)
1997 (1)

Location

France (4)
China (2)
Saudi Arabia (1)

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Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function

Antibiotics revolutionized medicine, however, it is now clear that broad-spectrum antibiotics alter the composition and function of the host’s microbiome. The microbiome plays a key role in human health and its perturbation is increasingly recognized as contributing to many human diseases. Wide spre...

2021-01-11 | MTBLS1257 | MetaboLights

Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Validation IgG 1:50]

Purpose: There is evidence that therapeutic cancer vaccines can lengthen survival for some cancer patients, but responses vary widely from one person to another. Methods to predict clinical outcomes will advance the field and provide new insights into critical determinants of in vivo efficacy. Thi...

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42163 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Validation IgM 1:50]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42175 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Validation Total Ig 1:50]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42176 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Validation Total Ig 1:200]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42179 | biostudies-arrayexpress

Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity

The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity" by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katha...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2024-08-26 | MSV000095695 | MassIVE

Baseline serum anti-glycan antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Training IgG 1:50]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42019 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Training IgM 1:50]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42020 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Training Total Ig 1:50]

ORGANISM(S): Homo sapiens

2013-04-01 | E-GEOD-42145 | biostudies-arrayexpress

Baseline serum anti-glycan antibodies of 28 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine [Training Total Ig 1:200]