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CHEBI ID

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CHEBI:68579 (1)
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Metabolite Name

Choline (17)
Adenine (16)
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L-Phenylalanine (12)
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Guanine (11)
L-Valine (11)
L-Methionine (11)

First Public Date

2026 (45)
2025 (31)
2024 (23)
2022 (21)
2023 (14)
2021 (14)
2020 (10)
2019 (8)
2015 (7)
2018 (6)
2014 (6)
2017 (3)
2013 (1)

Modelling Approach

Ordinary differential equation model (2)
Delayed differential equation model (1)

Study status

Withdrawn (1)
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Lab affiliation

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (38)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (11)
Centre for Proteome Research, University of Liverpool, Liverpool, UK (9)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (9)
IRCCS Istituto G Gaslini (6)
Baylor College of Medicine (4)
Institute of Bioinformatics , International Technology Park, Bangalore, India (4)
University of Alabama at Birmingham, O'Neal Mass Spectrometry Proteomics Shared Facility (4)
University of Liverpool (4)
1School of Natural Sciences, Macquarie University, Sydney, NSW, Australia 2Institute for Glyco-core Research (iGCORE), Nagoya University, Aichi, Japan (3)
Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver V5Z 1L3, Canada. (3)
Centre de recherche du Centre Hospitalier Universitaire (CHU) de Quebec-Université Laval, Québec, QC, Canada Centre de recherche sur le cancer de l’Université Laval, Québec, QC, Canada PROTEO-Quebec Network for Research on Protein Function, Engineering, and Applications, Québec, QC, Canada Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, QC, Canada (3)
Dept. of Laboratory Medicine, University of California, San Francisco, CA (3)
Edinburgh Cancer Research, CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK (3)
Faculty of Medicine, University of Ottawa, Ottawa, ON Canada (3)
Functional Proteomics, ICR (3)
Indiana University School of Medicine (3)
Institute of Clinical Medicine in National Yang-Ming Chiao Tung University, Taiwan (Muh-Hwa Yang Lab) (3)
Key Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, Institute of Brain Functional Genomics, School of Life Science and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, China (3)
National Institute for Bioprocessing Research and Training (3)
Amphista Therapeutics Cambridge United Kingdom (2)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (2)
Cambridge Institute for Medical Research, University of Cambridge (2)
Centre de Recherche en Cancérologie de Marseille, CRCM Inserm UMR1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes 27 Boulevard Leï Roure CS30059 13273 Marseille Cedex 09 France (2)
Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, University of Sydney, Camperdown, NSW, Australia (2)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, 28220 Madrid, Spain (2)
Chronic Disease Programme, UFIEC, Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain. (2)
Daglig leder, PROMEC Institutt for klinisk og molekylær medisin lars.hagen@ntnu.no 73598508 72573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 (2)
Department of Biochemistry and Molecular Biology and the Biomedicine Discovery Institute; Monash University; Clayton 3800; Victoria; Australia (2)
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, 75390, TX, USA (2)

Keyword

Omega-3 fatty acid (1)
Fish oil (1)
Gut microbiota (1)
Nutrition (1)
Tumor microenvironment (1)
Polyp (1)
Eicosapentaenoic acid ethyl ester (1)
Immune response (1)

IsPrivate

False (4)

Modification

-17.026549 (1)
15.994915 (1)
2x(15)N labeled L-lysine (1)
4'-dihydroxyphenylalanine (1)
4-tetrahydrothiazine-3-carboxylic acid (1)
42.010565 (1)
4x(15)N labeled L-arginine (1)
4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (42)
RNA-seq of coding RNA (20)
ChIP-seq (14)
Comparative genomic hybridization by array (7)
RNA-seq of non coding RNA (4)
Methylation profiling by high throughput sequencing (3)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
Interventional (2)
Unknown experiment type (1)
ChIP-chip by tiling array (1)
MBD-seq (1)
Bisulfite-seq (1)
DNA-seq (1)

Release Date

2022 (306)
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2013 (52)
2012 (40)
2011 (34)
2010 (28)
2009 (17)
2008 (13)
2007 (4)
2005 (3)
2006 (2)
2004 (2)
2002 (1)
1999 (1)
1998 (1)

Location

China (1)
United States (1)

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Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Mass spectrometry imaging (MSI) visualises molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labelling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. D...

2020-10-30 | MTBLS2075 | MetaboLights

Therapeutic Effect of Modified Meridian-Guided Acupoint Pressing on Lumbar Facet Joint Osteoarthritis: An Integrated Microbiomics and Metabolomics Analysis

Lumbar facet joint osteoarthritis (LFJ OA) is a leading cause of chronic low back pain, with limited effective long-term treatments due to the side effects of pharmacological interventions. Modified Meridian-Guided Acupoint Pressing (MMGAP), a Traditional Chinese Medicine (TCM) physical therapy, has...

2026-06-22 | MTBLS14816 | MetaboLights

Tumour sampling method can significantly influence gene expression profiles derived from neoadjuvant window studies II

Background: Gene expression profiling has been used extensively within breast cancer research. Patient matched transcriptomic studies of tumour samples before and after treatment offer great potential and have been initiated, but tend not to include a control group. Here we examine gene expression c...

ORGANISM(S): Homo sapiens

2016-08-08 | E-GEOD-76727 | biostudies-arrayexpress

Molecular Mechanisms Limiting the Therapeutic Window of AAV Gene Therapy in Mouse Models of Blue Cone Monochromacy

PRJNA1223411 | ENA

Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer.

Not available

S-EPMC6557781 | biostudies-literature

Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting

PRJNA762698 | ENA

Augmenting the therapeutic window of radiotherapy: A perspective on molecularly targeted therapies and nanomaterials.

Not available

S-EPMC8493937 | biostudies-literature