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TranscriptomicsExpression profiles of the hippocampus of Rsk2-KO mice
Coffin–Lowry Syndrome (CLS) is a syndromic form of mental retardation caused by loss of function mutations in the X-linked RPS6KA3 gene, which encodes Rsk2, a serine/threonine kinase involved in spatial memory. We analyzed hippocampal gene expression profiles in Rsk2-KO mice to identify changes in ...
ORGANISM(S): Mus musculus 
2010-12-22 | E-GEOD-22137 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of murine embryos lacking endogenous retinoic acid signaling
Retinoic acid (RA), an active derivative of the liposoluble vitamin A (retinol), acts as an important signaling molecule during embryonic development, regulating phenomenons as diverse as anterior-posterior axial patterning, forebrain and optic vesicle development, specification of hindbrain rhombom...
ORGANISM(S): Mus musculus 
2013-03-31 | E-GEOD-43578 | biostudies-arrayexpress
TranscriptomicsMolar and incisor development
One of the key questions in developmental biology is how from universally shared molecular mechanisms and pathways, is it possible to generate organs displaying similar or complementary functions, with a wide range of different shapes or tissue organization? The dentition represents a valuable syste...
ORGANISM(S): Mus musculus 
2013-03-31 | E-GEOD-43144 | biostudies-arrayexpress
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