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Although natural antibodies (NAbs) are present from birth, little is known about what drives their selection, and whether they have housekeeping functions. We now show that the prototypic T15-NAb, first identified because of its protective role in infection, is representative of a previously unknown...
ORGANISM(S): unidentified 
COL2A1-associated skeletal dysplasias and growth disorders affect cartilage extracellular matrix and endochondral growth, but patient growth-plate tissue is largely inaccessible, limiting non-invasive modelling of disease- and growth-factor-responsive molecular programs. Here, we generated chondroge...
ORGANISM(S): Homo sapiens 
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