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Bacteria are constantly exposed to fluctuations in reactive oxygen species (ROS). In particular, pathogenic bacteria encounter elevated ROS-levels during host infection. In our present study we investigated the intricate regulatory interplay of the LysR-type transcriptional regulators LsrB and OxyR ...
ORGANISM(S): Escherichia coli 
2025-04-28 | PXD055627 | Pride
The strictly anaerobic bacterium C. difficile has become one of the most problematic hospital acquired pathogens and a major burden for health care systems. Although antibiotics work effectively in most C. difficile infections (CDIs), their detrimental effect on the intestinal microbiome paves the w...
ORGANISM(S): Peptoclostridium difficile (strain 630) (Clostridium difficile) 
2018-03-05 | PXD007278 | Pride
This is the model with unfitted parameters described in the article Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Kl...
2024-09-02 | BIOMD0000000247 | BioModels
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