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TranscriptomicsInteractions between H2O2 and glutathione in gene expression
rs08-03_glutathion - glutathion - How does glutathione content or reduction state affect H2O2-induced changes in the transcriptome? - Three single Arabidopsis mutants were used: cat2, knockout for catalase2 and so enriched in H2O2; cad2, defective in glutathione content; cytGR, knockout for cytosoli...
ORGANISM(S): Arabidopsis thaliana 
2010-07-22 | E-GEOD-21424 | biostudies-arrayexpress
TranscriptomicsFunctions and adaptive responses to oxidative stress of the thioredoxin and glutathione pathways in Clostridium acetobutylicum
Oxidative stress is harmful for organism and occurs when the cells exposed to superoxid, hydrogen peroxide and alkylhydroperoxides. In microorganism, the glutathione- and thioredoxin-dependent reduction systems are universal and play an important role in response to defending oxidative stress. The _...
ORGANISM(S): Clostridium acetobutylicum ATCC 824 
2015-04-13 | E-MTAB-2747 | biostudies-arrayexpress
ProteomicsSpecificity and dynamics of H2O2 detoxification by the cytosolic redox regulatory network as revealed by in vitro reconstitution
The thiol redox state is a decisive functional characteristic of proteins in cell biology. Plasmatic cell compartments maintain a thiol-based redox regulatory network linked to the glutathione/glutathione disulfide couple (GSH/GSSG) and the NAD(P)H system. The basic network constituents are known an...
ORGANISM(S): Escherichia Coli 
2025-01-21 | PXD048374 | JPOST Repository
TranscriptomicsEssential Role of Thioredoxin and Glutathione in Pancreas
Acute pancreatitis (AP) is defined by acute inflammatory injury to the pancreas and oxidative stress has been implicated as a mechanistic driver of disease progression. To delineate the contribution of reactive oxygen species (ROS) detoxification pathways in AP, we employed a genetic model of pancre...
ORGANISM(S): Mus musculus 
2025-08-30 | E-MTAB-15511 | biostudies-arrayexpress
GenomicsEssential Role of Thioredoxin and Glutathione in Pancreas
Essential Role of Thioredoxin and Glutathione in Pancreas
PRJEB96295 | ENA
UnknownCharacterizing roles for the glutathione reductase, thioredoxin reductase and thioredoxin peroxidase-encoding genes of Magnaporthe oryzae during rice blast disease.
Not available
S-EPMC3901745 | biostudies-literature
UnknownHepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase.
Not available
S-EPMC5730093 | biostudies-literature
GenomicsDeletion of thioredoxin reductase disrupts redox homeostasis and impairs β-cell function
Deletion of thioredoxin reductase disrupts redox homeostasis and impairs β-cell function
PRJNA827778 | ENA
UnknownStructural analysis of glutaredoxin domain of Mus musculus thioredoxin glutathione reductase.
Not available
S-EPMC3530482 | biostudies-literature
UnknownInhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.
Not available
S-EPMC7293542 | biostudies-literature
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