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TranscriptomicsscRNA-seq analysis of cell subpopulations of the bronchoalveolar lavage fluid of healthy dogs
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
2020-06-29 | E-MTAB-9265 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of osteoblastic cells derived from human mesenchymal stem cells, incubated with secreted factors release by adipocytes against non-incubated controls
Our preliminary findings lead us to propose bone marrow adipocyte secretions as new actors of bone loss. Indeed, using a coculture model based on human bone marrow stromal cells, we previously showed that soluble factors secreted by adipocytes induced the conversion of osteoblasts towards an adipocy...
ORGANISM(S): Homo sapiens 
2021-01-05 | E-MTAB-8849 | biostudies-arrayexpress
TranscriptomicsIdentification of pro-fibrotic macrophages populations by scRNA-seq in West Highland white terriers affected with canine idiopathic pulmonary fibrosis
We used the scRNA-seq to characterize disease-related heterogeneity within cell populations of macrophages/monocytes in the bronchoalveolar lavage fluid from West Highland white terriers either healthy or affected with canine idioapthic pulmonary fibrosis. The disease is still not well understood, o...
ORGANISM(S): Canis lupus familiaris 
2020-12-02 | E-MTAB-9623 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of cell subpopulations of the healthy canine lung
We used the scRNA-seq to establish a comprehensive molecular cell atlas of the healthy canine lung, expanding our knowledge of lung cell subpopulations in dogs, and providing the molecular foundation for investigating lung cell identities and functions in lung diseases across species.
ORGANISM(S): Canis lupus familiaris 
2025-02-27 | E-MTAB-14296 | biostudies-arrayexpress
MetabolomicsEffect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Depression is the leading cause of disability worldwide. Recent observations have revealed an association between mood disorders and alterations of the intestinal microbiota, but causality remains yet to be established. Here, using unpredictable chronic mild stress (UCMS) as a mouse mod...

2021-01-21 | MTBLS121 | MetaboLights
UnknownLAB-STEM CELLS
Not available
S-EPMC3488793 | biostudies-literature
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