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OtherA Method for Large-scale Identification of Protein Arginine Methylation
PASSEL ID: PASS00081. Original data file: B100910_042.mzXML. Data published as part of Mol Cell Proteomics. 2012 11:1489-99 . From the Abstract: {{i}} ... Here we show that most tryptic peptides containing methylated arginine(s) are highly basic and hydrophilic. Consequently, they could be consider...
ORGANISM(S): Human 
GPM11210008866 | GPMDB
TranscriptomicsDiscovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circu...
ORGANISM(S): Ovis aries 
2010-05-15 | E-GEOD-17401 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
UnknownImproved survival after transplantation of more donor plasmacytoid dendritic or naive T cells from unrelated-donor marrow grafts: results from BMTCTN 0201.
Not available
S-EPMC4180368 | biostudies-literature
ProteomicsDiversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain
Amyloid-beta (Aβ) plays a key role in the pathogenesis of Alzheimer’s disease (AD), but little is known about the proteoforms present in human AD brain. We used high-resolution mass spectrometry to analyze intact, undigested Aβ from purified soluble aggregates and insoluble material in brains of 6 c...
ORGANISM(S): Homo sapiens (Human) 
2017-08-28 | PXD006552 | Pride
Post-translational modifications (ptms) Amyloid-beta Proteoforms Alzheimer’s disease Top-down mass spectrometry Truncations 
ProteomicsPulsed SILAC proteomics analysis of Escherichia coli RPL11 methyltransferase PrmA mutant
For the pulse-chase experiment, E. coli BW25113 and its isogenic delta prmA strains were grown in M9 minimal medium and L-Lysine-2HCl (13C6, 15N2) was added to cultures in exponential and stationary phase. The cells were cultured for an additional 2 hr and harvested. Proteins from the wild-type and ...
ORGANISM(S): Escherichia Coli Bw25113 (ncbitaxon:679895) 
2024-04-05 | MSV000094475 | MassIVE
TranscriptomicsFMR1 targets distinct mRNA sequence elements to regulate protein expression [PAR-CLIP]
Fragile-X Syndrome (FXS) is a multi-organ disease leading to mental retardation, macro-orchidism in males, and premature ovarian insufficiency in female carriers. FXS is also a prominent monogenic disease associated with autism spectrum disorders (ASD). FXS is typically caused by the loss of FRAGILE...
ORGANISM(S): Homo sapiens 
2012-12-13 | E-GEOD-39682 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast as telomeres shorten in trt1- strains, and to compare survivors with linear and circular chromosomes
Time course experiment to watch RNA expression profiles as telomeres shorten in trt1- strains, and to compare survivors with linear and circular chromosomes.
ORGANISM(S): Schizosaccharomyces pombe 
2005-03-01 | E-MEXP-201 | biostudies-arrayexpress
TranscriptomicsGene Expression differences in Hepatic Parenchyma and Portal Tracts in Hepatitis C Virus Infected Subjects with High and Low Fibrosis
Background & Aims: Chronic hepatitis C virus (HCV) infection is complicated by hepatic fibrosis. Hypothesizing that fibrogenic signals may originate in cells susceptible to HCV infection, gene expression of hepatocytes was analyzed from persons with chronic HCV at different stages of liver fibrosi...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-33650 | biostudies-arrayexpress
UnknownAgonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer.
Not available
S-EPMC4331004 | biostudies-literature
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