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ModelsKarim2021 - CardioTox net: Ligand-based prediction of hERG blockade
A robust predictor for hERG channel blockade based on an ensemble of five deep learning models. The authors have collected a dataset from public sources, such as BindingDB and ChEMBL on hERG blockers and non-blockers. The cut-off for hERG blockade was set at IC50 Model Type: Predictive machine lea...
2024-07-18 | MODEL2407180003 | BioModels
Machine Learning Model FAIR-AIML Ersilia 
UnknownMatthew-Wood syndrome is caused by truncating mutations in the retinol-binding protein receptor gene STRA6.
Not available
S-EPMC1867105 | biostudies-literature
TranscriptomicsDNA copy number profiling of canine osteosarcoma
Identification of DNA copy number imbalances in 22 spontaneous canine osteosarcoma cases using array comparative genomic hybridization (aCGH) analysis
ORGANISM(S): Canis familiaris 
2013-11-01 | E-MTAB-1986 | biostudies-arrayexpress
TranscriptomicsWidespread over-expression of the X chromosome in sterile F1 hybrid mice
We used a reciprocal cross of Mus musculus and M. domesticus in which F1 males are sterile in one direction and fertile in the other direction, in order to associate expression differences with sterility. Four different crosses were performed. A cross between two strains within each mouse species (M...
ORGANISM(S): Mus musculus musculus x M. m. domesticus 
2010-10-05 | E-GEOD-17684 | biostudies-arrayexpress
UnknownComputerized Cognitive Training for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors: A Randomized Controlled Trial.
Not available
S-EPMC4652013 | biostudies-literature
TranscriptomicsTranscription profiling of organs in the Rhesus Macaque
Cross organ comparison. Probes made 10/22/04, slide hybes 10/25/04, scanned 10/26/04.
ORGANISM(S): Macaca mulatta 
2004-08-30 | E-TABM-9 | biostudies-arrayexpress
TranscriptomicsArgonaute2 mediates compensatory expansion of the pancreatic M-CM-^_-cell
Pancreatic M-CM-^_-cells adapt to compensate for the increased metabolic demand during insulin resistance. While the microRNA pathway has an essential role in the expansion of M-CM-^_-cell mass, the extent of its contribution is unclear. Here we show that miR-184 is silenced in the pancreatic islets...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-46623 | biostudies-arrayexpress
ModelsRichards2016 - Genome-scale metabolic reconstruction of Methanococcus maripaludis (iMR539)
Richards2016 - Genome-scale metabolic reconstruction of Methanococcus maripaludis (iMR539) This model is described in the article: Exploring Hydrogenotrophic Methanogenesis: a Genome Scale Metabolic Reconstruction of Methanococcus maripaludis. Richards MA, Lie TJ, Zhang J, R...
2024-10-15 | BIOMD0000001099 | BioModels
FROG 
TranscriptomicsTuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
Tuberculosis (TB) remains a major public health problem and we lack a comprehensive understanding of how Mycobacterium tuberculosis (M. tb) infection impacts host immune responses. We compared, at two timepoints, the induced immune response to TB antigen, BCG and IL-1β stimulation between latently M...
ORGANISM(S): Homo sapiens 
2022-11-05 | E-MTAB-12379 | biostudies-arrayexpress
UnknownNeurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma.
Not available
S-EPMC3462045 | biostudies-literature
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