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DNA microarrays were used to provide a global transcriptional profile of S. typhimurium during the intracellular growth phase of infection pathogenesis following infection of macrophages.
ORGANISM(S): Salmonella enterica serovar Typhimurium 
StpA is a paralogue of the nucleoid associated protein H-NS that is conserved in a range of enteric bacteria and had no known function in Salmonella enterica serovar Typhimurium. Here, we show that 5% of the Salmonella genome is regulated by StpA, which contrasts with the situation in Escherichia co...
ORGANISM(S): Salmonella typhimurium SL1344 
StpA is a paralogue of the nucleoid associated protein H-NS that is conserved in a range of enteric bacteria and had no known function in Salmonella enterica serovar Typhimurium. Here, we show that 5% of the Salmonella genome is regulated by StpA, which contrasts with the situation in Escherichia co...
ORGANISM(S): Salmonella typhimurium SL1344 
We used ChIP-chip analysis to identify where the nucleoid associated protein StpA binds on the Salmonella Typhimurium genome. We identified 285 chromosomal regions bound by StpA, ranging in size from 400 to 3500 base pairs and containing 572 genes. Comparison of the ChIP data revealed that StpA disp...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
This SuperSeries is composed of the following subset Series: GSE18424: The effect of stpA deletion on S. Typhimurium gene expression during growth in rich medium GSE18428: StpA prevents RpoS-dependent transcription during mid-exponential growth in S. Typhimurium GSE18450: Identification of StpA-bind...
ORGANISM(S): Salmonella typhimurium SL1344 
The expression profile of an S. Typhimurium mutant strain unable to synthesise ppGpp (relAspoT deletions) was compared to the wild-type strain. The effect of ppGpp on virulence gene expression was studied under 4 different growth conditions that induce virulence gene expression. Keywords: genetic mo...
ORGANISM(S): Salmonella typhimurium 
Transcriptional profiling of early stationary phase S. Typhimurium, comparing wild type SL1344 with an isogenic ∆relA,∆spoT strain (JH3370). Each array used labelled cDNA against a common genomic DNA reference. The wild type strain was arrayed in triplicate and the ∆relA,∆spoT strain in quadruplicat...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
S. Typhimurium 112910a parental strain and an isogenic M-NM-^TscsA strain were grown to stationary phase in SPI2 inducing minimal medium (MM5.8 - Erikkson et al., 2006 Inf & Imm., 74:1243) with or without supplementation with 1M-BM-5M cortisol 4 samples (stat phase wt, stat phase wt + 1M-BM-5M corti...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
Transcriptional profiling of log and stationary phases of S. Typhimurium, comparing wild type with the ∆scsA strain. Each array used labelled cDNA against a common genomic DNA reference. Triplicate arrays were carried out for each of the 4 conditions: wild type log phase, wild type stationary phase,...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
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