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GenomicsOverexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer
Androgen receptor (AR) is overexpressed in the majority of castration-resistant prostate cancers (CRPCs). Our goal was to study the effect of AR overexpression on the chromatin binding of the receptor and to identify AR target genes that may be important in the emergence of CRPC. We have established...
ORGANISM(S): Homo sapiens 
2013-06-27 | E-GEOD-48308 | biostudies-arrayexpress
UnknownSWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.
Not available
S-EPMC4417730 | biostudies-literature
UnknownAbatacept Pharmacokinetics and Exposure Response in Patients Hospitalized With COVID-19: A Secondary Analysis of the ACTIV-1 IM Randomized Clinical Trial.
Not available
S-EPMC11046337 | biostudies-literature
UnknownPhase III Intergroup Trial of Adjuvant Androgen Deprivation With or Without Mitoxantrone Plus Prednisone in Patients With High-Risk Prostate Cancer After Radical Prostatectomy: SWOG S9921.
Not available
S-EPMC5959197 | biostudies-literature
UnknownRegulation of mixotrophy in <i>Synechocystis</i> by a rhomboid protease.
Not available
S-EPMC12944812 | biostudies-literature
UnknownCirculating tumor cell counts are prognostic of overall survival in SWOG S0421: a phase III trial of docetaxel with or without atrasentan for metastatic castration-resistant prostate cancer.
Not available
S-EPMC3970171 | biostudies-literature
TranscriptomicsMassively Parallel Reporter Assay (MPRA) of 175 bp human genomic fragments containing variants in high LD with lead variants from asthma GWAS.
We performed a massively parallel reporter assay (MPRA) of 2,034 genomic regions containing single nucleotide polymorphisms (4,587 regions tested with 96,328 barcodes) that are in high linkage disequilibrium with lead variants from an asthma GWAS (PMID: 31036433). Test sequences were transfected int...
ORGANISM(S): Homo sapiens 
2025-03-11 | E-MTAB-14273 | biostudies-arrayexpress
UnknownSurvival outcomes and risk group validation from SWOG S0925: a randomized phase II study of cixutumumab in new metastatic hormone-sensitive prostate cancer.
Not available
S-EPMC7423720 | biostudies-literature
UnknownIncreased Expression of Lamin A/C Correlate with Regions of High Wall Stress in Abdominal Aortic Aneurysms.
Not available
S-EPMC4851850 | biostudies-literature
UnknownA novel meningococcal outer membrane vesicle vaccine with constitutive expression of FetA: A phase I clinical trial.
Not available
S-EPMC4535279 | biostudies-literature
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