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Saccharomyces cerevisiae is a eukaryotic model organism widely used for the investigation of fundamental cellular processes and disease mechanisms. Consequently, the lipid landscape of yeast has been extensively investigated and up to this day the lipidome is considered as rather basic. Here, we use...
2021-01-08 | MTBLS2119 | MetaboLights
A major challenge to the study of tumor DNA copy number (CN) in clinical specimens is the lack of appropriate fresh frozen samples and thus a dependence on Formalin-Fixed Paraffin Embedded (FFPE) banked samples, which typically have more extensive clinical follow up information. However, on most hi...
ORGANISM(S): Homo sapiens 
UQCRH, also called the hinge protein, is a small subunit of Ubiquinol—cytochrome-c reductase (complex III). Here we used a complexome analysis of primary and immortalized fibroblasts from patients with a homozygous 2 exon deletion in the UQCRH gene and analyzed complex III assembly and altered supe...
ORGANISM(S): Homo sapiens (Human) 
2021-09-20 | PXD022856 | Pride
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