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TranscriptomicsTranscription profiling of Drosophila DHR96 nuclear receptor mutants
DHR96 is a Drosophila member of the CAR/PXR/LXR family of Nuclear receptors. To Identify potential target genes for the DHR96 nuclear receptor we used microarray analysis to identify genes that were mis-regulated relative to control animals in the DHR96 mutant. Experiment Overall Design: Total RNA w...
ORGANISM(S): Drosophila melanogaster 
2009-10-27 | E-GEOD-18576 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila dHNF4 null mutant larvae fed or starved for 24h
We show that dHNF4 null mutant larvae are sensitive to starvation. Starved mutant larvae consume glycogen normally, but retain lipids in their midgut and fat body, and have increased levels of long chain fatty acids, suggesting that they are unable to efficiently mobilize stored fat for energy. HNF4...
ORGANISM(S): Drosophila melanogaster 
2009-01-31 | E-GEOD-14531 | biostudies-arrayexpress
TranscriptomicsMicroarray experiment to identify gene expression changes in response to Phenobarbital treatment and CncC overexpression in Drosophila.
Transcriptional profiling of mature adult w1118 males treated with phenobarbital compared to controls and heat treated HS-CncC flies compared with heat treated w1118 flies. Mature adult w1118 males were treated witheither 5% sucrose alone or 5% sucrose supplemented with 0.3% phenobarbital for six ho...
ORGANISM(S): Drosophila melanogaster 
2011-11-29 | E-GEOD-30087 | biostudies-arrayexpress
TranscriptomicsExpression data from Drosophila melanogaster err mutant animals vs. wild type animals at a mid-second instar larval time
Cancer cells utilize a unique form of aerobic glycolysis, called the Warburg effect, to efficiently produce the macromolecules required for proliferation. Here we show that a metabolic program related to the Warburg effect is used during normal Drosophila development and regulated by the fly orthol...
ORGANISM(S): Drosophila melanogaster 
2011-02-02 | E-GEOD-23336 | biostudies-arrayexpress
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