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Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors.
Not available
S-EPMC7845944
|
biostudies-literature
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Transcriptional Silencing of MCL-1 Through Cyclin-Dependent Kinase Inhibition in Acute Myeloid Leukemia.
Not available
S-EPMC6920180
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biostudies-literature
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Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies.
Not available
S-EPMC3975838
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biostudies-literature
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The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
Not available
S-EPMC6265654
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biostudies-literature
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Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924
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biostudies-literature
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Ex vivo activity of BCL-2 family inhibitors ABT-199 and ABT-737 combined with 5-azacytidine in myeloid malignancies.
Not available
S-EPMC4331188
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biostudies-literature
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PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation.
Not available
S-EPMC3385948
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biostudies-literature
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Functional proteomic profiling of AML predicts response and survival.
Not available
S-EPMC2951831
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Safety, pharmacokinetics, and preliminary efficacy of E6201 in patients with advanced solid tumours, including melanoma: results of a phase 1 study.
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S-EPMC6008465
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biostudies-literature
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Safety and efficacy of the maximum tolerated dose of givinostat in polycythemia vera: a two-part Phase Ib/II study.
Not available
S-EPMC7387307
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