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MetabolomicsMetabolic abnormalities of the cortico-striato-thalamo-cortical circuit of rats with tic disorder

Tic disorder (TD) is a developmental neuropsychiatric disorder that primarily occurs during childhood and impacts the quality of life and psychosocial function of patients. The pathogenesis of TD involves the dysregulation of the cortico-striato-thalamo-cortical (CSTC) circuit and metabolic abnor...

2025-03-18 | MTBLS11764 | MetaboLights
TranscriptomicsExpression data from highly purified MMTV-Neu Tumor Initiating Cells (TICs) and the non-TIC CD24- fraction
The cancer stem cell model maintains that tumors are organized in a hierarchy driven by tumor initiating cells (TICs), and that patient survival inversely correlates with TIC gene expression. Here we generated a prognostic signature for HER2+ breast cancer from TICs purified from MMTV-Her2/Neu mamma...
ORGANISM(S): Mus musculus 
2011-05-28 | E-GEOD-29590 | biostudies-arrayexpress
TranscriptomicsDawn anticipation
To investigate the role of TIC in the morning perception process, we performed a transcriptome analysis of the wild type and time for coffee mutant (tic-2) at dawn. An additional file is included. In this file, the expression values for the replicates are condensed in a single data point obtaining o...
ORGANISM(S): Arabidopsis thaliana 
2013-10-10 | E-MTAB-1362 | biostudies-arrayexpress
ProteomicsThe chloroplast outer and inner envelope membrane translocase (TOC/TIC) interaction network identifies a 23 kDa glycine-rich protein as new subunit of the 1-MDa TIC complex
The protein import machinery is essential for chloroplast biogenesis, but knowledge on its exact functioning and the subunits involved in protein translocation is incomplete. Using TAP-tagged Toc159, we reproducibly identified a translocase interaction network that comprises in addition to known TOC...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-02-22 | PXD008469 | Pride
Arabidopsis thaliana Tic 
GenomicsZFHX4 and CHD4 ChIP sequencing in glioblastoma tumor initiating cells
Glioblastomas (GBM) harbor subpopulations of therapy-resistant tumor initiating cells (TICs) that are self-renewing and multipotent. To understand the regulation of the TIC state, we performed an image-based screen for genes regulating GBM TIC maintenance and identified ZFHX4, a 397-kDa transcriptio...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-52419 | biostudies-arrayexpress
GenomicWhole Exome Sequencing in Tourette Disorder in Simplex Trios-TIC Genetics

The Tourette International Collaborative Genetics (TIC Genetics) Study is an international collaboration of scientists and clinicians specialized in Tourette Disorder (TD) from more than 20 sites across the United States, Europe, and South Korea. The study was established to further our understan...

phs001423 | dbGaP
ProteomicsQuantification of Tic-Toc subunits in gun1
Quantification of Tic-Toc subunits in the wild type and gun1-101 mutants in the control conditions and treated with lincomycin or norflurazon to determine if there are differences between genotypes.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-04-23 | PXD013005 | Pride
Norflurazon Arabidopsis Wild type Gun1-101 Lincomycin 
GenomicsTIC regulates hypocotyl growth in Arabidopsis by inhibiting PHYA signal
TIC regulates hypocotyl growth in Arabidopsis by inhibiting PHYA signal
PRJNA656425 | ENA
UnknownCase report: Advice for schools on managing functional tic-like behaviours.
Not available
S-EPMC9760715 | biostudies-literature
TranscriptomicsGenomic alteration in MRC5-derived induced pluripotent stem (MRC5-iPS) cell line, Tic
Disease-specific induced pluripotent stem (iPS) cells have been used for a model to analyze pathogenesis of the disease. We generated iPS cells derived from a fibroblastic cell line of ataxia telangiectasia (AT-iPS cells). In analysis of AT-iPS cells, the human wild-type iPS cell line (MRC5-iPS) was...
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-49082 | biostudies-arrayexpress
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