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TranscriptomicsMesp1 induces a subset of hematopoietic-associated transcription factors in ES cell-derived Flk1+Tie2+ endothelium
Previously, we reported that the transcription factor Mesp1 promotes the cell fates of cardiomyocytes, smooth muscle, and vascular endothelium. Recently, hematopoietic stem cells (HSCs) were shown to derive from hemogenic endothelium. Since Mesp1 regulates development of endothelium, it potentially...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-34537 | biostudies-arrayexpress
TranscriptomicsDual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation
This SuperSeries is composed of the following subset Series: GSE34537: Mesp1 induces a subset of hematopoietic-associated transcription factors in ES cell-derived Flk1+Tie2+ endothelium GSE34541: Identification of gene targets of Meis2 GSE34543: Identification of gene targets of Meis1 Refer to indiv...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-34583 | biostudies-arrayexpress
TranscriptomicsUnraveling the molecular basis of temperature-dependent genetic regulation in Penicillium marneffei
Comparative analysis of transcriptome of Penicillium marneffei PM1 grown at 25°C and 37°C Penicillium marneffei strain PM1 was pre-cultured at 25°C and 37°C for two weeks on Sabouraud's Dextrose Agar (SDA). Messenger RNAs were then isolated from one-week 25°C and 37°C cultures and sequenced with Il...
ORGANISM(S): Talaromyces marneffei PM1 
2013-07-20 | E-GEOD-48898 | biostudies-arrayexpress
UnknownOptimization of Fermentation Conditions for Antarctic Bacteria and Investigation of Its Antimicrobial Mechanism Against <i>Klebsiella pneumoniae</i>.
Not available
S-EPMC12472101 | biostudies-literature
TranscriptomicsGene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray
Osteoarthritis (OA) is a complex degenerative joint disease, which is not only a cartilage but also a bone disease. A better understanding of the early molecular mechanism changes of subchondral bone in vivo may contribute to elucidating the pathogenesis of OA. We used microarray technology to inves...
ORGANISM(S): Rattus norvegicus 
2012-12-11 | E-GEOD-30322 | biostudies-arrayexpress
UnknownNlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates.
Not available
S-EPMC10764762 | biostudies-literature
TranscriptomicsProtective unfolded protein response in human pancreatic beta cells transplanted into mice
Islet transplantation exposes beta cells to mild hyperglycemia and to the abnormal environment of the transplant site. These conditions may affect beta cells and induce the expression of genes involved in beta cell damage. Gene expression profile of human beta cells exposed to mild hyperglycemia by ...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-22097 | biostudies-arrayexpress
UnknownAblation of macrophage transcriptional factor FoxO1 protects against ischemia-reperfusion injury-induced acute kidney injury.
Not available
S-EPMC12254786 | biostudies-literature
UnknownStructural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Not available
S-EPMC11589576 | biostudies-literature
TranscriptomicsTranscription profiling of mouse P5 cerebellum to investigate conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of neuroblastoma
Identification of common mechanisms underlying organ development and primary tumor formation should yield new insights into tumor biology and facilitate the generation of relevant cancer models. We have developed a novel method to project the gene expression profiles of medulloblastomas (MBs)—human ...
ORGANISM(S): Mus musculus 
2009-01-30 | E-GEOD-14514 | biostudies-arrayexpress
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