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TranscriptomicsColonic gene expression data of TIMP1 knock out colitis mice
Increased levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) have been detected in fibrotic strictures in Crohn’s disease. In a murine model of chronic inflammation, fibrosis was associated with an increase in TIMP-1 and inhibition of matrix metalloproteinase (MMP)-mediated degradation. We...
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-73424 | biostudies-arrayexpress
GenomicsA SNF2 protein targets variable copy number repeats and thereby influences allele-specific expression
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-22162 | biostudies-arrayexpress
UnknownMapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering.
Not available
S-EPMC2373703 | biostudies-literature
UnknownRelationship of polymorphisms in the tissue inhibitor of metalloproteinase (TIMP)-1 and -2 genes with chronic heart failure.
Not available
S-EPMC6013444 | biostudies-literature
UnknownAssociation of COL4A3 (rs55703767), MMP-9 (rs17576)and TIMP-1 (rs6609533) gene polymorphisms with susceptibility to type 2 diabetes.
Not available
S-EPMC5403448 | biostudies-literature
UnknownMycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation.
Not available
S-EPMC4293239 | biostudies-literature
UnknownGenetic susceptibility of early aseptic loosening after total hip arthroplasty: the influence of TIMP-1 gene polymorphism on Chinese Han population.
Not available
S-EPMC4324875 | biostudies-literature
UnknownAssociation between TIMP-2 gene polymorphism and breast cancer in Han Chinese women.
Not available
S-EPMC6518501 | biostudies-literature
UnknownCoexistence of proangiogenic potential and increased MMP-9, TIMP-1, and TIMP-2 levels in the plasma of patients with critical limb ischemia.
Not available
S-EPMC6656566 | biostudies-literature
TranscriptomicsMatrix metalloproteinase-9 and TIMP-1 in peripheral nerve: Implications for myelin formation
Remyelination is a key step in functional nerve regeneration performed by Schwann cells (SC). We have demonstrated that matrix metalloproteinase (MMP)-9 is a major regulator of signal transduction and phenotypic switching in SCs. Herein, genome-wide transcriptional profiling, followed by Ingenuity P...
ORGANISM(S): Mus musculus 
2012-02-28 | E-GEOD-33454 | biostudies-arrayexpress
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